{"id":"W4283388413","doi":"10.1097/wno.0000000000001634","title":"Leber Hereditary Optic Neuropathy With Childhood Onset Producing Severe Unilateral Optic Neuropathy With No Relative Afferent Pupillary Defect","year":2022,"lang":"en","type":"article","venue":"Journal of Neuro-Ophthalmology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Leber's hereditary optic neuropathy; Optic neuropathy; Medicine; Afferent; Pupil; Optic nerve; Ophthalmology; Audiology; Neuroscience; Psychology; Anatomy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000380836,0.0004559197,0.000585374,0.0002368143,0.0003270623,0.00003076113,0.0004490895,0.0001511679,0.0003250163],"category_scores_gemma":[0.0003053413,0.0003551775,0.0002649072,0.000295046,0.0001785324,0.00003230511,0.0003280556,0.001223783,0.00001831319],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004485536,"about_ca_system_score_gemma":0.0003455381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000655928,"about_ca_topic_score_gemma":0.000001731346,"domain_scores_codex":[0.9962112,0.001443732,0.0006269659,0.0007607742,0.000416468,0.0005408059],"domain_scores_gemma":[0.9980536,0.0001415,0.0006743199,0.000598375,0.0002964051,0.0002357865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"case_report","study_design_scores_codex":[0.03185108,0.003508281,0.2038554,0.0001970311,0.00176695,0.227116,0.002011139,0.04881333,0.4696063,0.0001408339,0.01076036,0.000373358],"study_design_scores_gemma":[0.00391792,0.04291803,0.07796744,0.000047046,0.0003335322,0.8664876,0.000179268,0.00007839258,0.00269238,0.00006412358,0.004592851,0.0007213745],"study_design_candidate":"case_report","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952863,0.0003451627,0.00008010481,0.0004859179,0.002319231,0.0004092194,0.0000335269,0.00001725405,0.00102327],"genre_scores_gemma":[0.9962074,0.00003008971,0.001069368,0.0007552408,0.0008444636,0.00002771366,0.00007369631,0.0001059895,0.0008861008],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6393717,"threshold_uncertainty_score":0.99989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009773259064560265,"score_gpt":0.2188730908462016,"score_spread":0.2090998317816413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}