{"id":"W4283453521","doi":"10.3390/cancers14122887","title":"The Extracellular Matrix Stiffening: A Trigger of Prostate Cancer Progression and Castration Resistance?","year":2022,"lang":"en","type":"review","venue":"Cancers","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre; Université Laval; Hôtel-Dieu de Québec","funders":"Canadian Institutes of Health Research; Fonds de Recherche du Québec - Santé; Prostate Cancer Foundation","keywords":"Prostate cancer; Medicine; Cancer; Prostate; Disease; Stiffening; Oncology; Internal medicine; Extracellular matrix; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003641602,0.0004712494,0.0009678131,0.001329771,0.0002248672,0.001097797,0.000501472,0.0008481034,0.003422168],"category_scores_gemma":[0.0007862782,0.0001819499,0.0005557063,0.001473829,0.0003593299,0.0009037007,0.0004764294,0.001022197,0.0009894072],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004052333,"about_ca_system_score_gemma":0.001108503,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001092774,"about_ca_topic_score_gemma":0.002209372,"domain_scores_codex":[0.9998063,0.00004039312,0.00003056882,0.000033615,0.00006919804,0.00001992548],"domain_scores_gemma":[0.9997436,0.0001277566,0.00004739517,0.000005582085,0.00005916007,0.00001650881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000137813,0.00005312037,0.0007394354,0.04234492,0.0002522777,0.0003352157,0.0001445032,0.0003338508,0.00211453,0.004439671,0.02974084,0.9193639],"study_design_scores_gemma":[0.00002252553,0.0001679825,0.003161727,0.01332516,0.0003958555,0.002776591,0.0002309522,0.0001639717,0.0009696523,0.003095947,0.9756535,0.00003621016],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000150576,0.9989774,0.00004725851,0.000259632,0.0001032305,0.000002160344,0.00002050905,0.000003340445,0.0004359325],"genre_scores_gemma":[0.001004186,0.9984479,0.00005205526,0.0001393774,0.00008873572,0.000002019189,0.00002253594,6.661531e-7,0.0002424094],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003422168,"threshold_uncertainty_score":0.01144832,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06857487869890601,"score_gpt":0.4143794855158802,"score_spread":0.3458046068169742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}