{"id":"W4283456942","doi":"10.1053/j.gastro.2022.06.054","title":"Western-Style Diet, pks Island-Carrying Escherichia coli, and Colorectal Cancer: Analyses From Two Large Prospective Cohort Studies","year":2022,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Colorectal Cancer Screening and Detection","field":"Medicine","cited_by":109,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Janssen Pharmaceuticals; National Institute of Diabetes and Digestive and Kidney Diseases; Gilead Sciences; National Cancer Institute; Servier; National Institutes of Health; Conquer Cancer Foundation; George W. Stone Family Foundation; Huazhong University of Science and Technology; Japan Society for the Promotion of Science; Uehara Memorial Foundation; Cancer Research UK; Mitsukoshi Health and Welfare Foundation; Bayer Fund; Stand Up To Cancer; Entertainment Industry Foundation; Unum Therapeutics; Gary Bennett Family Fund; Merck; Pfizer; Dana-Farber Cancer Institute; Yasuda Memorial Medical Foundation; Bristol-Myers Squibb; Eli Lilly and Company; American Association for Cancer Research","keywords":"Colorectal cancer; Hazard ratio; Prospective cohort study; Escherichia coli; Internal medicine; Cancer; Microsatellite instability; Incidence (geometry); Proportional hazards model; Confidence interval; KRAS; Cohort; Medicine; Biology; Gastroenterology; Oncology; Microsatellite; Genetics; Gene; Allele","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000214625,0.0002075871,0.0005669541,0.0001132483,0.0003312783,0.00001455532,0.0000712147,0.00004237253,0.0002199376],"category_scores_gemma":[0.00003609097,0.0001970739,0.00009455792,0.0001761115,0.0001126732,0.00006387656,0.0003046934,0.0004150438,0.000002681979],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003195374,"about_ca_system_score_gemma":0.00003628891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0012679,"about_ca_topic_score_gemma":0.006476101,"domain_scores_codex":[0.9984111,0.0001881079,0.000250485,0.0004574821,0.0002313681,0.0004614692],"domain_scores_gemma":[0.9994429,0.0000697469,0.000143713,0.0001460065,0.00007923542,0.0001183647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01948242,0.00008450883,0.971458,0.00001529764,0.001139544,0.0000316363,0.001465051,0.00007048133,0.005723664,0.00000192536,0.0003370329,0.0001904156],"study_design_scores_gemma":[0.00401687,0.008341527,0.9824519,0.00002194503,0.0006780186,0.000093829,0.001712862,0.0006640035,0.001081876,0.00002552512,0.0007888349,0.0001228751],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940674,0.003745712,0.0002877309,0.0003855648,0.0006077798,0.0004812276,0.0002111824,0.0001050965,0.0001082938],"genre_scores_gemma":[0.9976851,0.0002360948,0.0001828673,0.0007415288,0.0003821961,0.0005775532,0.00005847609,0.00002570011,0.0001105029],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01546555,"threshold_uncertainty_score":0.8036442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02754267100613785,"score_gpt":0.3338918080117397,"score_spread":0.3063491370056019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}