{"id":"W4283456942","doi":"10.1053/j.gastro.2022.06.054","title":"Western-Style Diet, pks Island-Carrying Escherichia coli, and Colorectal Cancer: Analyses From Two Large Prospective Cohort Studies","year":2022,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Colorectal Cancer Screening and Detection","field":"Medicine","cited_by":109,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Janssen Pharmaceuticals; National Institute of Diabetes and Digestive and Kidney Diseases; Gilead Sciences; National Cancer Institute; Servier; National Institutes of Health; Conquer Cancer Foundation; George W. Stone Family Foundation; Huazhong University of Science and Technology; Japan Society for the Promotion of Science; Uehara Memorial Foundation; Cancer Research UK; Mitsukoshi Health and Welfare Foundation; Bayer Fund; Stand Up To Cancer; Entertainment Industry Foundation; Unum Therapeutics; Gary Bennett Family Fund; Merck; Pfizer; Dana-Farber Cancer Institute; Yasuda Memorial Medical Foundation; Bristol-Myers Squibb; Eli Lilly and Company; American Association for Cancer Research","keywords":"Colorectal cancer; Hazard ratio; Prospective cohort study; Escherichia coli; Internal medicine; Cancer; Microsatellite instability; Incidence (geometry); Proportional hazards model; Confidence interval; KRAS; Cohort; Medicine; Biology; Gastroenterology; Oncology; Microsatellite; Genetics; Gene; Allele","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001579374,0.001065553,0.0006492541,0.0008656321,0.001108912,0.001395966,0.0008196321,0.001404083,0.001687588],"category_scores_gemma":[0.002275415,0.001249095,0.001973456,0.001800464,0.0006308759,0.0006325018,0.001042953,0.001325309,0.0002590256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004291978,"about_ca_system_score_gemma":0.0005500724,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02146067,"about_ca_topic_score_gemma":0.0304364,"domain_scores_codex":[0.9987914,0.0004656277,0.0001183597,0.0003450619,0.00009821967,0.0001813814],"domain_scores_gemma":[0.9977419,0.0004852052,0.0005912521,0.0005300581,0.000226913,0.0004246398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001628658,0.0001197854,0.9945565,0.00003375695,0.001724657,0.0001330503,0.0001482538,0.00004362541,0.0007751565,0.0000362889,0.000159046,0.0006412689],"study_design_scores_gemma":[0.00009148454,0.0001920361,0.9982485,0.000008935511,0.0007053593,0.0001209465,0.000256239,0.0001030738,0.00005494396,0.00002206883,0.000186574,0.000009846965],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977048,0.0008471064,0.0002688562,0.00004952608,0.0000222059,0.00002459911,0.000777486,0.000006856086,0.000298492],"genre_scores_gemma":[0.9982943,0.0002855226,0.0003193219,0.00005572327,0.00002183661,0.00003924759,0.0006412638,0.000006657443,0.000336167],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02146067,"threshold_uncertainty_score":0.04267156,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02754267100613785,"score_gpt":0.3338918080117397,"score_spread":0.3063491370056019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}