{"id":"W4283516342","doi":"10.1111/bjh.18329","title":"Quality of life independently predicts overall survival in myelofibrosis: Key insights from the COntrolled MyeloFibrosis Study with ORal Janus kinase inhibitor Treatment <scp>(COMFORT)‐I</scp> study","year":2022,"lang":"en","type":"letter","venue":"British Journal of Haematology","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Myelofibrosis; Ruxolitinib; Medicine; Janus; Quality of life (healthcare); Janus kinase 2; Oncology; Internal medicine; Key (lock); Cancer research; Biology; Nanotechnology; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00859058,0.001180178,0.002898617,0.0007197707,0.0003217916,0.001538184,0.000765471,0.0009732327,0.002026455],"category_scores_gemma":[0.009758191,0.0003992778,0.005536333,0.00154826,0.000488445,0.0005380087,0.0008068159,0.001438174,0.0001776284],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004710875,"about_ca_system_score_gemma":0.0007073534,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00209804,"about_ca_topic_score_gemma":0.00376675,"domain_scores_codex":[0.9969577,0.00174419,0.0003568976,0.0004699825,0.0003388464,0.0001324664],"domain_scores_gemma":[0.9910171,0.005073844,0.002275246,0.0004957535,0.0006875532,0.0004504545],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1342595,0.0009478162,0.5633999,0.02211173,0.1556913,0.0003503783,0.0004189654,0.001703289,0.001576455,0.0007283795,0.006039131,0.1127732],"study_design_scores_gemma":[0.02605138,0.00760337,0.8187536,0.002898106,0.1324573,0.0003933858,0.0001780309,0.001538944,0.0004198401,0.001568748,0.007978947,0.0001582527],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5515766,0.4323515,0.001161764,0.002656316,0.0003445726,0.0005058985,0.009040261,0.00002550256,0.002337638],"genre_scores_gemma":[0.9501321,0.03762651,0.001196069,0.00134295,0.001037146,0.000485163,0.007834232,0.00001853898,0.0003273695],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00859058,"threshold_uncertainty_score":0.04543185,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03137900389653403,"score_gpt":0.2793989253585921,"score_spread":0.2480199214620581,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}