{"id":"W4283576233","doi":"10.1136/annrheumdis-2022-eular.164","title":"OP0034 IXEKIZUMAB IMPROVES SIGNS, SYMPTOMS, AND QUALITY OF LIFE IN PATIENTS WITH AXIAL SpA IRRESPECTIVE OF DISEASE DURATION: RESULTS FROM THE COAST-V, COAST-W AND COAST-X TRIALS","year":2022,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Medicine; Ixekizumab; Internal medicine; Axial spondyloarthritis; Demographics; Placebo; Physical therapy; Ankylosing spondylitis; Disease; Demography; Pathology; Secukinumab; Sacroiliitis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00148313,0.0007790242,0.002254152,0.0001967266,0.0002975134,0.0007432763,0.0005218628,0.000858883,0.002408818],"category_scores_gemma":[0.00140336,0.0002337085,0.003069837,0.0003523486,0.0005669082,0.0006343857,0.0003575212,0.001683655,0.0003099414],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004654093,"about_ca_system_score_gemma":0.0005817891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001370859,"about_ca_topic_score_gemma":0.003721608,"domain_scores_codex":[0.9994618,0.0002469581,0.00006503019,0.00007763827,0.0000648394,0.00008374405],"domain_scores_gemma":[0.9992205,0.0002442026,0.0002642919,0.00005767655,0.00007477201,0.0001384878],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8179455,0.0018699,0.01339473,0.006205533,0.01468306,0.0001590978,0.0001196803,0.0007381946,0.004617705,0.0002659569,0.004336387,0.1356642],"study_design_scores_gemma":[0.7849287,0.1014698,0.08815867,0.001345815,0.01527527,0.0006130518,0.0001937749,0.0007602664,0.001385434,0.0005670803,0.005224771,0.0000774635],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.93212,0.06062355,0.0002614337,0.0008892878,0.000275437,0.0003363457,0.001431223,0.00004401125,0.004018826],"genre_scores_gemma":[0.9788883,0.01570276,0.0005111896,0.0008730062,0.0003423577,0.0002325279,0.001730223,0.00001276058,0.001706851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002408818,"threshold_uncertainty_score":0.008058369,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04802140836017738,"score_gpt":0.3134336407927013,"score_spread":0.2654122324325239,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}