{"id":"W4283587040","doi":"10.1128/spectrum.00640-22","title":"Subinhibitory Concentrations of Antibiotics Exacerbate Staphylococcal Infection by Inducing Bacterial Virulence","year":2022,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Bacterial Identification and Susceptibility Testing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Health and Medical Research Fund; Food and Health Bureau; University Grants Committee","keywords":"Antibiotics; Virulence; Microbiology; Bacteremia; Tetracycline; Biology; In vivo; Peritonitis; Ampicillin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001490881,0.0003616745,0.0003209441,0.0001886979,0.0001379845,0.0003260784,0.0001437818,0.0003257786,0.003338052],"category_scores_gemma":[0.0002994107,0.0001190872,0.0001942746,0.0001020835,0.000215815,0.0001842302,0.0002953632,0.0008954774,0.0005206865],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001704884,"about_ca_system_score_gemma":0.0002166219,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003243635,"about_ca_topic_score_gemma":0.0008629177,"domain_scores_codex":[0.9996456,0.00008083486,0.00003497619,0.00004194522,0.0001169029,0.00007973091],"domain_scores_gemma":[0.9996313,0.00009156157,0.00008537733,0.00003708189,0.00005258525,0.0001021685],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003053343,0.0002032218,0.002373965,0.0001058877,0.00001186756,0.0003433654,0.00004572297,0.00005635838,0.9904062,0.00008559577,0.0002176819,0.005844784],"study_design_scores_gemma":[0.00003314031,0.006123981,0.06810644,0.0000642943,0.00005175473,0.00304148,0.0003885425,0.0005587842,0.9118816,0.0003407073,0.0093928,0.00001653734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895716,0.003900227,0.001175464,0.0003689982,0.0001767955,0.00003949441,0.0001703577,0.00006792959,0.004529106],"genre_scores_gemma":[0.9950414,0.001588481,0.001061723,0.0001701274,0.00007328372,0.00001747714,0.0001333744,0.00001307881,0.001901041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003338052,"threshold_uncertainty_score":0.01116687,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007810772119505395,"score_gpt":0.2205224070742702,"score_spread":0.2127116349547648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}