{"id":"W4283592329","doi":"10.1186/s13063-022-06405-7","title":"Australasian Malignant PLeural Effusion (AMPLE)-3 trial: study protocol for a multi-centre randomised study comparing indwelling pleural catheter (±talc pleurodesis) versus video-assisted thoracoscopic surgery for management of malignant pleural effusion","year":2022,"lang":"en","type":"article","venue":"Trials","topic":"Pleural and Pulmonary Diseases","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto; University Health Network","funders":"National Health and Medical Research Council; New South Wales Workers' Compensation Dust Disease Board","keywords":"Medicine; Pleurodesis; Malignant pleural effusion; Mesothelioma; Surgery; Video-assisted thoracoscopic surgery; Randomized controlled trial; Quality of life (healthcare); Cardiothoracic surgery; Adverse effect; Pleural effusion; Internal medicine; Nursing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.006577308,0.0008944119,0.003543457,0.0005696104,0.0008646994,0.0001114679,0.0005426419,0.0001222162,0.0002858228],"category_scores_gemma":[0.0008464107,0.0006825955,0.001650274,0.0006193338,0.00007874966,0.0002096545,0.0004960145,0.0003327627,0.000006169148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003143723,"about_ca_system_score_gemma":0.0002408473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002497858,"about_ca_topic_score_gemma":0.00007829441,"domain_scores_codex":[0.989764,0.002712821,0.003715315,0.001363321,0.001333193,0.001111313],"domain_scores_gemma":[0.9932697,0.003300917,0.001824892,0.0009207682,0.0002579656,0.0004257844],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9414321,0.02265924,0.01933963,0.002058088,0.001816875,0.0003902957,0.001510752,0.0002770571,0.005151549,0.00001164253,0.001184444,0.004168387],"study_design_scores_gemma":[0.9144478,0.01530315,0.04289575,0.0009622965,0.005105893,0.00002664256,0.01121642,0.004908429,0.002453327,0.00001803568,0.001568527,0.001093706],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6575168,0.00003369965,0.00009384653,0.0001380218,0.0008901925,0.340909,0.000259629,0.0001455908,0.0000132169],"genre_scores_gemma":[0.7160992,0.00000459738,0.0006745162,0.00003919993,0.0003212935,0.2817529,0.0003818595,0.0001159334,0.0006104551],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05915612,"threshold_uncertainty_score":0.9995625,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3402614474872064,"score_gpt":0.4464202863833608,"score_spread":0.1061588388961544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}