{"id":"W4283689111","doi":"10.1136/annrheumdis-2022-eular.2416","title":"POS0939 BIMEKIZUMAB IN PATIENTS WITH ACTIVE NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS: 24-WEEK EFFICACY & SAFETY FROM BE MOBILE 1, A PHASE 3, MULTICENTRE, RANDOMISED, PLACEBO‑CONTROLLED STUDY","year":2022,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"UCB Pharma","keywords":"Medicine; Axial spondyloarthritis; Placebo; Ankylosing spondylitis; BASDAI; Internal medicine; Clinical endpoint; Mallinckrodt; Randomized controlled trial; Gastroenterology; Sacroiliitis; Arthritis; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001492347,0.001606767,0.003344863,0.0004261646,0.0004871122,0.001043777,0.0007982589,0.002201849,0.004982003],"category_scores_gemma":[0.001375723,0.0007802834,0.002254284,0.0003896083,0.00105372,0.001402644,0.0003648035,0.002909699,0.001367597],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004652075,"about_ca_system_score_gemma":0.0007009575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004986514,"about_ca_topic_score_gemma":0.001112054,"domain_scores_codex":[0.9994203,0.000250718,0.00004908771,0.0001049947,0.0000642577,0.0001107285],"domain_scores_gemma":[0.9992232,0.0001994266,0.0002106739,0.0000575886,0.00005383879,0.0002551958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9620523,0.005724108,0.001463689,0.0009310591,0.001063131,0.00007658234,0.000064174,0.0002709663,0.00451943,0.00006371074,0.001082745,0.02268818],"study_design_scores_gemma":[0.8800595,0.1104276,0.007407858,0.00005981747,0.0005422432,0.00007575315,0.0000402826,0.000249776,0.0003776907,0.0000822994,0.0006519194,0.00002520929],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852391,0.009479425,0.000289141,0.0006308386,0.000452673,0.001103866,0.0009466104,0.00009725271,0.001761047],"genre_scores_gemma":[0.9891223,0.003801276,0.0006733375,0.001226355,0.000569001,0.001171435,0.001098893,0.00001966488,0.002317692],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004982003,"threshold_uncertainty_score":0.01666641,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0188048056202932,"score_gpt":0.2849293935157176,"score_spread":0.2661245878954244,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}