{"id":"W4283690415","doi":"10.1177/15330338221109650","title":"Pattern of Recurrence of Glioblastoma Versus Grade 4 IDH-Mutant Astrocytoma Following Chemoradiation: A Retrospective Matched-Cohort Analysis","year":2022,"lang":"en","type":"article","venue":"Technology in Cancer Research & Treatment","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; University Health Network; Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Isocitrate dehydrogenase; IDH1; Astrocytoma; Medicine; Nuclear medicine; Pathology; Glioma; Oncology; Chemistry; Mutant; Cancer research; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004672246,0.000219953,0.0009165021,0.002265437,0.0001550292,0.000006325386,0.0002410194,0.0001184293,0.0002885968],"category_scores_gemma":[0.00007434102,0.0001955004,0.0003114372,0.005262662,0.0002537287,0.00004330744,0.0002130623,0.0004252505,0.000003922763],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004637173,"about_ca_system_score_gemma":0.0003712234,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003513838,"about_ca_topic_score_gemma":0.001756279,"domain_scores_codex":[0.9972624,0.0001338589,0.0004835666,0.0005985108,0.0009980769,0.0005236509],"domain_scores_gemma":[0.9986696,0.0001591459,0.0002046905,0.0006981199,0.0001805438,0.00008786192],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001227489,0.002401038,0.9714569,0.00002918426,0.00400801,0.0007180039,0.0005951343,0.000204442,0.005724149,0.0001393633,0.000030457,0.01346583],"study_design_scores_gemma":[0.01488767,0.01846981,0.5291696,0.0001563635,0.002116971,0.0000369865,0.003361283,0.0005325997,0.4304211,0.0004537833,0.0001540991,0.0002397367],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933897,0.002099116,0.000005718993,0.002979169,0.00009900617,0.001138375,0.0001618121,0.00005361575,0.00007349048],"genre_scores_gemma":[0.9958002,0.0006043726,0.0001468238,0.000006119245,0.00001781382,0.00335011,0.00003528648,0.00002131092,0.0000179576],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4422873,"threshold_uncertainty_score":0.9991838,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05066799599414054,"score_gpt":0.3958923464090491,"score_spread":0.3452243504149086,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}