{"id":"W4283690623","doi":"10.1136/annrheumdis-2022-eular.219","title":"POS1015 SAFETY OF GUSELKUMAB IN PATIENTS WITH ACTIVE PSORIATIC ARTHRITIS WHO ARE BIO-NAÏVE OR TNFi-EXPERIENCED: POOLED RESULTS FROM 4 RANDOMIZED CLINICAL TRIALS THROUGH 2 YEARS","year":2022,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Medicine; Psoriatic arthritis; Adverse effect; Internal medicine; Population; Placebo; Golimumab; Randomized controlled trial; Surgery; Arthritis; Rheumatoid arthritis; Adalimumab; Pathology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005119021,0.001826893,0.006211421,0.000673134,0.0003832642,0.002052688,0.0007107838,0.002119221,0.003478626],"category_scores_gemma":[0.003246252,0.0009787052,0.008345571,0.0009509887,0.001216492,0.002234654,0.000634875,0.003115002,0.0007443831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000708556,"about_ca_system_score_gemma":0.000778564,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005186984,"about_ca_topic_score_gemma":0.001149756,"domain_scores_codex":[0.997508,0.001422137,0.000258502,0.0003887413,0.000176004,0.0002465446],"domain_scores_gemma":[0.9980399,0.0008113848,0.0005711702,0.0001757084,0.0001234537,0.0002782732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.940567,0.0007899042,0.002698057,0.002455603,0.02401522,0.00005835675,0.00003943869,0.001036962,0.002686718,0.0001063505,0.0006073839,0.02493898],"study_design_scores_gemma":[0.8272049,0.1033309,0.02155388,0.000461818,0.04216953,0.0001610658,0.0001170501,0.00105644,0.001326855,0.0006021332,0.001911387,0.0001040022],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9273901,0.06348933,0.001491198,0.0007746416,0.001061503,0.0008660154,0.001960801,0.0001803893,0.002785966],"genre_scores_gemma":[0.9844502,0.01009194,0.000692478,0.0008793054,0.0004336577,0.0005200474,0.001758187,0.0000315141,0.001142788],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006211421,"threshold_uncertainty_score":0.02707231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0590640130460358,"score_gpt":0.3336205587870653,"score_spread":0.2745565457410294,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}