{"id":"W4283692756","doi":"10.1136/annrheumdis-2022-eular.2682","title":"POS1563-PARE SELF-MANAGEMENT STRATEGIES FOR ADVERSE DRUG REACTIONS AS REPORTED BY TNF-ALPHA INHIBITOR USERS: AN OBSERVATIONAL STUDY","year":2022,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta Hospital","funders":"","keywords":"Medicine; Etanercept; Adalimumab; Injection site; Cohort; Drug reaction; Observational study; Cohort study; Internal medicine; Drug; Disease; Pharmacology; Tumor necrosis factor alpha","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001694611,0.00045613,0.0007252634,0.000655886,0.0006432621,0.001066592,0.0004296145,0.001171787,0.002348565],"category_scores_gemma":[0.005056483,0.0004797717,0.002129953,0.001331891,0.0004115088,0.0008896146,0.0005672919,0.001773112,0.0005637591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006293032,"about_ca_system_score_gemma":0.0007522359,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002131874,"about_ca_topic_score_gemma":0.002343216,"domain_scores_codex":[0.9977919,0.0007637341,0.0004448814,0.0004664104,0.0002869274,0.0002461561],"domain_scores_gemma":[0.9922133,0.00159086,0.004656533,0.0005531461,0.0003917201,0.0005944536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003898193,0.0007215622,0.9915184,0.0001061512,0.0008295138,0.0001379732,0.0001548134,0.00004191815,0.000229828,0.00003043947,0.0001535938,0.002177574],"study_design_scores_gemma":[0.000477921,0.002991691,0.9935604,0.00006079516,0.0007174386,0.0006637878,0.000442388,0.0002756988,0.0001388022,0.00006579343,0.0005724697,0.00003288102],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985411,0.0005064333,0.00009172228,0.00003487114,0.00001345514,0.00004137781,0.0004538257,0.000002377328,0.0003148244],"genre_scores_gemma":[0.9986811,0.0002320812,0.0001397219,0.0001086724,0.00002453999,0.00004385959,0.0005729222,0.000002553095,0.0001945564],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002348565,"threshold_uncertainty_score":0.008962035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1169170567836122,"score_gpt":0.3767668613203753,"score_spread":0.2598498045367632,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}