{"id":"W4283706185","doi":"10.1136/annrheumdis-2022-eular.1074","title":"AB0046 RESISTANCE TO OXIDATIVE DEGRADATION OF A FORMULATION COMBINING HYALURONIC ACID AND NIACINAMIDE","year":2022,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Alberta Innovates; Killam Trusts; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Hyaluronic acid; Synovial fluid; Medicine; Niacinamide; Oxidative stress; Biochemistry; Osteoarthritis; Chemistry; Nicotinamide; Enzyme; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002997292,0.0002850102,0.0001871816,0.0001750275,0.0001400063,0.0002235502,0.000212393,0.00026768,0.003006418],"category_scores_gemma":[0.000397123,0.0001291591,0.0002365831,0.0001325688,0.000156343,0.0001889691,0.0001316548,0.0004666247,0.0003056291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000124294,"about_ca_system_score_gemma":0.0002202365,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001002603,"about_ca_topic_score_gemma":0.0008507655,"domain_scores_codex":[0.9997304,0.00008762516,0.00002549294,0.00003803003,0.00005830474,0.00006010117],"domain_scores_gemma":[0.9998189,0.00004423765,0.00004274591,0.0000211446,0.00003833221,0.00003464794],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001047475,0.0001818171,0.0001295098,0.00004391606,0.00001436522,0.00007262934,0.00001882767,0.00007881698,0.9948277,0.00004552155,0.00007667376,0.003462754],"study_design_scores_gemma":[0.00009093292,0.003642729,0.001826183,0.000007795948,0.00003380952,0.0002048738,0.00002339885,0.0007180118,0.9914246,0.00001919597,0.002003171,0.000005369013],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971433,0.0007177774,0.0008626086,0.00005745054,0.00004219127,0.00002791727,0.00007600608,0.00002278007,0.001049957],"genre_scores_gemma":[0.9944891,0.0003405957,0.001642677,0.00003725633,0.00001348827,0.00001717647,0.0003033875,0.00001611584,0.003140265],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003006418,"threshold_uncertainty_score":0.01005751,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02988436072981294,"score_gpt":0.2895248712868131,"score_spread":0.2596405105570002,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}