{"id":"W4283708528","doi":"10.1038/s41590-022-01239-6","title":"Overcoming the LAG3 phase problem","year":2022,"lang":"en","type":"letter","venue":"Nature Immunology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Swiss National Centre of Competence in Research Kidney Control of Homeostasis; Australian Research Council; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Chemistry; Cancer research; Cell biology; Computational biology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005519287,0.0008420801,0.001240727,0.0006305862,0.002893535,0.004128795,0.001512186,0.04428321,0.004727427],"category_scores_gemma":[0.02873843,0.0005723984,0.001221608,0.0003924726,0.004098979,0.004345909,0.002369225,0.05193875,0.005823572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003467147,"about_ca_system_score_gemma":0.003297355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001572276,"about_ca_topic_score_gemma":0.002390239,"domain_scores_codex":[0.9969886,0.001008342,0.0002737547,0.000354222,0.0009643069,0.0004108142],"domain_scores_gemma":[0.9899302,0.006603585,0.0004944975,0.0004630123,0.001263689,0.001245157],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009577617,0.0000468608,0.0003183947,0.00006580051,0.00002388064,0.00181068,0.00008472917,0.0001288046,0.0002982169,0.01140318,0.9669939,0.01872976],"study_design_scores_gemma":[0.0003015292,0.00011861,0.0003977674,0.0001961937,0.00003584358,0.001873457,0.0001694131,0.0007731548,0.000561281,0.05984029,0.9356821,0.00005036258],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0003674144,0.00225244,0.0004498003,0.9700444,0.02408406,0.000009615663,0.00002199956,0.00004014382,0.002730207],"genre_scores_gemma":[0.007442032,0.001658948,0.0006189669,0.9240353,0.06093562,0.00004478837,0.00001901247,0.00003120434,0.005214253],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.04428321,"threshold_uncertainty_score":0.02918911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01127974782105173,"score_gpt":0.2948007885940209,"score_spread":0.2835210407729692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}