{"id":"W4283712894","doi":"10.1136/annrheumdis-2022-eular.2765","title":"AB0149 RNA SEQUENCING OF SKIN BIOPSY SAMPLES REVEALS UNIQUE BIOLOGICAL PROCESSES AMONG SPECIFIC GROUPS OF ADULT PATIENTS WITH IgA VASCULITIS","year":2022,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Vasculitis and related conditions","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"AstraZeneca (Canada)","funders":"Pfizer","keywords":"Medicine; Skin biopsy; Biopsy; Transcriptome; KEGG; Fold change; Vasculitis; Internal medicine; Pathology; Gene; Biology; Disease; Genetics; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001792322,0.0001894833,0.0002458908,0.0005155619,0.0003288155,0.0005342017,0.0001131541,0.0003405188,0.001487683],"category_scores_gemma":[0.0005952479,0.00008592188,0.0001987032,0.0003165157,0.0001987648,0.0001355929,0.0001800912,0.0002391586,0.000288105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000131802,"about_ca_system_score_gemma":0.0001069831,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007355227,"about_ca_topic_score_gemma":0.001107083,"domain_scores_codex":[0.9997242,0.00004577079,0.00002900647,0.00008349661,0.0000396454,0.00007790084],"domain_scores_gemma":[0.9997644,0.00008177591,0.00005575399,0.00001786114,0.00003561959,0.0000445492],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001645308,0.0001227177,0.7207108,0.00007242245,0.0001215029,0.001934758,0.0006498494,0.0001954741,0.2564025,0.0001457701,0.0004100252,0.01758896],"study_design_scores_gemma":[0.00001460978,0.0002763194,0.9908162,0.00001101746,0.00004598969,0.002103716,0.0004923383,0.0004150087,0.005026429,0.0001110758,0.0006824016,0.000004939177],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988694,0.0001816537,0.0002285072,0.0000337555,0.000006781785,0.000005605016,0.0001725519,0.000006966853,0.0004947395],"genre_scores_gemma":[0.9991361,0.00005934386,0.0002318822,0.00005966841,0.00001475054,0.00000726258,0.0002798354,0.000004195449,0.0002070005],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001487683,"threshold_uncertainty_score":0.004976749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02910047224857671,"score_gpt":0.2477823952946258,"score_spread":0.2186819230460491,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}