{"id":"W4283713536","doi":"10.1038/s41541-022-00498-6","title":"A chimeric thermostable M2e and H3 stalk-based universal influenza A virus vaccine","year":2022,"lang":"en","type":"article","venue":"npj Vaccines","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Virology; Virus; Influenza A virus; Influenza vaccine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001322868,0.0002328664,0.0001698211,0.0000945549,0.0000918088,0.0001367993,0.00020074,0.0002885129,0.0007084304],"category_scores_gemma":[0.00006501106,0.00008626916,0.0002185848,0.00007275811,0.0001472394,0.0001574283,0.0002388927,0.0003071495,0.0002280448],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003128818,"about_ca_system_score_gemma":0.0001652472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000550662,"about_ca_topic_score_gemma":0.0006892476,"domain_scores_codex":[0.9999425,0.000008009764,0.00000407021,0.00001292752,0.00001410814,0.00001844433],"domain_scores_gemma":[0.9999592,0.000003731437,0.00001168083,0.00000514709,0.000007596169,0.00001256719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005624731,0.00001917302,0.0002235569,0.00001699507,0.000004800672,0.00002278862,0.000007135116,0.0001242761,0.9986286,0.00007757902,0.00002375364,0.0007952654],"study_design_scores_gemma":[0.00003660956,0.0009409203,0.004701749,0.0000083673,0.00002571945,0.0004617948,0.00002441058,0.002002257,0.986808,0.00006302218,0.004920049,0.000007150553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99245,0.0007146286,0.005963976,0.00004576819,0.00001930292,0.00003502696,0.0001782747,0.00004880355,0.000544247],"genre_scores_gemma":[0.9925639,0.0002634557,0.005166863,0.0000469014,0.000004620357,0.00002484412,0.0003721816,0.000008391374,0.001548796],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007084304,"threshold_uncertainty_score":0.00236994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04630088801781754,"score_gpt":0.333857234830777,"score_spread":0.2875563468129594,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}