{"id":"W4283721139","doi":"10.1093/humrep/deac107.566","title":"P-616 Systematic review and meta-analysis of efficacy and safety of r-FSH biosimilars EMA-approved compared to reference r-FSH (follitropin alfa)","year":2022,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Ovarian function and disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Biosimilar; Medicine; Randomized controlled trial; Meta-analysis; Systematic review; Cochrane Library; Confidence interval; Internal medicine; MEDLINE; Gynecology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001164088,0.0001567331,0.001805484,0.0003498243,0.0002865859,0.00000699714,0.00008113139,0.00002999632,0.0006437851],"category_scores_gemma":[0.0003974892,0.0001295862,0.0002527153,0.0009428301,0.00007538151,0.00003953321,0.0002607084,0.0001239669,0.000001270272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003840871,"about_ca_system_score_gemma":0.00002471151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000524261,"about_ca_topic_score_gemma":0.00001740262,"domain_scores_codex":[0.9977776,0.0002911335,0.0008218247,0.000605695,0.0003891293,0.0001146469],"domain_scores_gemma":[0.9983099,0.00003820482,0.0004350912,0.0009401556,0.0001938262,0.00008280101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.004241756,0.004438385,0.002006543,0.5288707,0.3581171,0.00001552177,0.01297977,0.001422481,0.05234533,0.009292125,0.02487859,0.001391729],"study_design_scores_gemma":[0.002975264,0.001192328,0.01435406,0.001297368,0.9712549,0.00007177539,0.002566826,0.0001042947,0.0008727159,0.0001778883,0.004630862,0.0005017259],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6097073,0.2960284,0.001645946,0.05540001,0.0006034073,0.02687444,0.0005178605,0.0004809276,0.008741735],"genre_scores_gemma":[0.9961233,0.000529561,0.0002783228,0.001220876,0.00001488523,0.0001586703,0.0001223445,0.0000169562,0.00153514],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6131378,"threshold_uncertainty_score":0.7048995,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09465529882219034,"score_gpt":0.3248182386259564,"score_spread":0.230162939803766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}