{"id":"W4283722589","doi":"10.1002/hep.32634","title":"HBV transcription and translation persist despite viral suppression in HBV‐HIV co‐infected patients on antiretroviral therapy","year":2022,"lang":"en","type":"article","venue":"Hepatology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"Pfizer; National Institute of Allergy and Infectious Diseases; National Institute on Alcohol Abuse and Alcoholism; National Institute of Diabetes and Digestive and Kidney Diseases; Gilead Sciences; National Institutes of Health","keywords":"HBcAg; HBsAg; Medicine; HBeAg; Hepatitis B; Virology; cccDNA; Viral load; Hepatitis B virus; Immunohistochemistry; Immunology; Human immunodeficiency virus (HIV); Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001468689,0.0001782047,0.0003773439,0.0002755865,0.0002326317,0.000007596337,0.00005084723,0.0001019316,0.0002382779],"category_scores_gemma":[0.00003294266,0.0001696688,0.00007143351,0.0001850147,0.0001061885,0.00008455055,0.00001823705,0.0003387505,0.00001547519],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001420605,"about_ca_system_score_gemma":0.00003956238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005057608,"about_ca_topic_score_gemma":0.0002654413,"domain_scores_codex":[0.9984654,0.000338342,0.000295333,0.000344288,0.0002598785,0.0002967518],"domain_scores_gemma":[0.999617,0.00006976361,0.00006692349,0.0001481396,0.0000380491,0.00006015968],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001378416,0.0003963529,0.969559,0.00002749126,0.00002711025,0.0000406914,0.002172923,0.000003078204,0.01248484,0.00007110158,0.000599527,0.01323945],"study_design_scores_gemma":[0.006974387,0.003451559,0.9756201,0.00003039466,0.00003295742,0.00002314125,0.00008530224,0.002005671,0.002033008,0.00004214008,0.009510389,0.0001909654],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969476,0.0004296455,0.00002456965,0.0006356476,0.0002516615,0.0005853147,0.00008163142,0.00006463344,0.0009793303],"genre_scores_gemma":[0.9982991,0.0003689882,0.00006402818,0.0007476949,0.00002873418,0.00008744037,0.00032433,0.00002543822,0.00005425006],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01304849,"threshold_uncertainty_score":0.6918893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02916832351840662,"score_gpt":0.2821949932379123,"score_spread":0.2530266697195057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}