{"id":"W4283744395","doi":"10.1016/s2352-3026(22)00173-9","title":"Thromboprophylactic low-molecular-weight heparin versus standard of care in unvaccinated, at-risk outpatients with COVID-19 (ETHIC): an open-label, multicentre, randomised, controlled, phase 3b trial","year":2022,"lang":"en","type":"article","venue":"The Lancet Haematology","topic":"Heparin-Induced Thrombocytopenia and Thrombosis","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"LEO Pharma; Daiichi Sankyo Europe; Sanofi; Bayer HealthCare; University of Oxford; National Institute for Health and Care Research; Norgine; Bristol-Myers Squibb; AstraZeneca; Amgen; Pfizer; GlaxoSmithKline","keywords":"Medicine; Low molecular weight heparin; Population; Clinical endpoint; Randomized controlled trial; Adverse effect; Internal medicine; Clinical trial; Surgery; Pediatrics; Heparin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001233043,0.001434779,0.002982199,0.000361019,0.0003905074,0.001114106,0.0009743506,0.001818592,0.005559086],"category_scores_gemma":[0.002031885,0.0005329237,0.001739697,0.0004259524,0.001215632,0.000862272,0.0003982174,0.003225923,0.0006222964],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008062196,"about_ca_system_score_gemma":0.0008784048,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001545401,"about_ca_topic_score_gemma":0.002849112,"domain_scores_codex":[0.9992747,0.0003956246,0.00003931769,0.0001187121,0.00004911347,0.00012265],"domain_scores_gemma":[0.9991417,0.0003062798,0.0001869384,0.00005284765,0.00004132156,0.000270984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9809021,0.003483478,0.0004727623,0.0007589302,0.0009460057,0.00003133372,0.00004290224,0.0001571392,0.001016737,0.0000872181,0.0005373859,0.01156395],"study_design_scores_gemma":[0.9580308,0.03961157,0.001304872,0.00004687566,0.0003258769,0.00002366349,0.00002202569,0.0002157912,0.0001019825,0.00008810242,0.0002194881,0.000009046113],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98716,0.007889811,0.0004513286,0.0006598933,0.0006802872,0.001236804,0.0006104272,0.00007697714,0.00123448],"genre_scores_gemma":[0.9891593,0.003704656,0.001216946,0.001103589,0.0005266208,0.001709949,0.0007520925,0.0000189906,0.00180782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005559086,"threshold_uncertainty_score":0.01859701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06402574084759774,"score_gpt":0.3857780231439044,"score_spread":0.3217522822963067,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}