{"id":"W4283744400","doi":"10.3390/curroncol29070368","title":"Gynecologic Cancer Risk and Genetics: Informing an Ideal Model of Gynecologic Cancer Prevention","year":2022,"lang":"en","type":"review","venue":"Current Oncology","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Women's College Hospital; University of Toronto; Centre hospitalier universitaire de Québec; Simon Fraser University; BC Cancer Agency; McGill Genome Centre; McGill University; University of British Columbia","funders":"National Institute for Health and Care Research; Barts Charity","keywords":"Summit; Medicine; Lynch syndrome; Cancer prevention; Population; Genetic testing; Family medicine; Psychological intervention; Cancer; Endometrial cancer; Gynecologic cancer; Gynecology; Ovarian cancer; Gerontology; Environmental health; Colorectal cancer; Internal medicine; Nursing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002386384,0.0009427821,0.0009775688,0.001906022,0.0007007996,0.001812621,0.001288491,0.003002533,0.003240263],"category_scores_gemma":[0.003056346,0.0003285041,0.0006404073,0.001742298,0.002099649,0.003025871,0.001128155,0.005716541,0.001275119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.006606969,"about_ca_system_score_gemma":0.01517589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.08125316,"about_ca_topic_score_gemma":0.1189547,"domain_scores_codex":[0.9992372,0.0002772693,0.00005613524,0.00005379171,0.0002901512,0.0000855172],"domain_scores_gemma":[0.9986689,0.0005707684,0.00008218978,0.00003237185,0.0005107549,0.0001351031],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007310094,0.00006789673,0.0005629577,0.01495411,0.0001136075,0.0002579377,0.0003982565,0.0004692647,0.0005146996,0.03914857,0.2217233,0.7217163],"study_design_scores_gemma":[0.00001586142,0.00002960784,0.0008883373,0.009134698,0.00006180521,0.0003777473,0.0002801417,0.00009323467,0.000077706,0.007243093,0.981781,0.00001670412],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005930045,0.9799452,0.0002186473,0.01674497,0.001042727,0.000006461712,0.00001914343,0.00001489474,0.001948737],"genre_scores_gemma":[0.0009828695,0.9939681,0.0005288074,0.00336543,0.000436443,0.000005883471,0.00003099545,0.000002663481,0.0006787296],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.08125316,"threshold_uncertainty_score":0.1615605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1715835846890914,"score_gpt":0.460161589340085,"score_spread":0.2885780046509936,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}