{"id":"W4283745319","doi":"10.1093/jas/skac235","title":"Sustained vascular contractile response induced by an R- and S-epimer of the ergot alkaloid ergocristine and attenuation by a noncompetitive antagonist","year":2022,"lang":"en","type":"article","venue":"Journal of Animal Science","topic":"Plant and fungal interactions","field":"Agricultural and Biological Sciences","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Ministry of Agriculture - Saskatchewan","keywords":"Phenoxybenzamine; Epimer; Antagonist; Vasoconstriction; Chemistry; Contraction (grammar); Stereochemistry; Alkaloid; Pharmacology; Internal medicine; Endocrinology; Biology; Receptor; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001637938,0.0003018806,0.0002860795,0.00009692704,0.0001034578,0.0001589477,0.0001852733,0.0003121232,0.00119451],"category_scores_gemma":[0.0001368152,0.0001843181,0.0003095711,0.0001057252,0.0002237596,0.0001933466,0.0001526115,0.000637621,0.0002541792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001964397,"about_ca_system_score_gemma":0.0001720238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004008842,"about_ca_topic_score_gemma":0.0009667809,"domain_scores_codex":[0.9998796,0.00002308171,0.000007572297,0.00002236644,0.00002236074,0.00004486286],"domain_scores_gemma":[0.9998517,0.00003842351,0.00003797459,0.00001732266,0.00001954464,0.00003491544],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002042702,0.00001994986,0.00006141725,0.00001599151,0.000002927402,0.00004468954,0.000008338853,0.000006849208,0.9993069,0.00001070451,0.00000884996,0.0003089436],"study_design_scores_gemma":[0.00002810291,0.00397887,0.02017679,0.000008977484,0.00003265477,0.0003837726,0.0000646006,0.000416043,0.9740272,0.00001731697,0.0008605638,0.000005063182],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997117,0.0008084815,0.0006869714,0.00005296203,0.0000197285,0.00001944286,0.0000744497,0.00001825215,0.001202723],"genre_scores_gemma":[0.9936904,0.0009438967,0.002199933,0.0001187178,0.00004020864,0.00004538403,0.0003721022,0.000008772902,0.00258063],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00119451,"threshold_uncertainty_score":0.003996015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01126433592858385,"score_gpt":0.236147515656486,"score_spread":0.2248831797279022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}