{"id":"W4283749404","doi":"10.1093/humrep/deac106.066","title":"O-277 Understanding mosaicism origin through non-invasive PGT","year":2022,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Forensic and Genetic Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"CReATe Fertility Centre","funders":"","keywords":"Biology; Genetics; Computational biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003450997,0.0002075488,0.0001879162,0.0004067144,0.0002516982,0.0009236311,0.0003641305,0.0005710878,0.004145629],"category_scores_gemma":[0.0006515514,0.0001524888,0.000225208,0.0001873556,0.0007539762,0.000734358,0.0006389749,0.0007229198,0.0007638475],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002803956,"about_ca_system_score_gemma":0.0003195062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008882982,"about_ca_topic_score_gemma":0.00119694,"domain_scores_codex":[0.9998273,0.00003315507,0.000007768989,0.00004949229,0.00005499744,0.00002740378],"domain_scores_gemma":[0.999686,0.0001392577,0.00006959883,0.00005143165,0.00002963018,0.00002402891],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002302146,0.00009374796,0.02510146,0.0002692927,0.00003530217,0.002469486,0.0004923399,0.001079081,0.834523,0.02045576,0.0009304268,0.1143199],"study_design_scores_gemma":[0.0000440177,0.0004982075,0.0823905,0.0002211508,0.0001550072,0.01696159,0.001582138,0.0127349,0.7690938,0.04647319,0.06978845,0.00005699476],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7982305,0.006601357,0.1254866,0.001685765,0.0001625073,0.000126021,0.0007057541,0.0004726903,0.06652875],"genre_scores_gemma":[0.9699856,0.003518273,0.01604914,0.0003172952,0.000046194,0.00002609018,0.0003145028,0.00009753097,0.009645347],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004145629,"threshold_uncertainty_score":0.01386851,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07794158717248696,"score_gpt":0.327061935087511,"score_spread":0.249120347915024,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}