{"id":"W4283762428","doi":"10.1016/b978-0-323-91706-3.00011-4","title":"The tumor microenvironment of colorectal cancer liver metastases: Molecular mediators and future therapeutic targets","year":2022,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"","keywords":"Immune system; Metastasis; Colorectal cancer; Tumor microenvironment; Cancer research; Homeostasis; Liver cancer; Cancer; Biology; Medicine; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007524448,0.0002425744,0.0001879348,0.0002666548,0.0001067433,0.0008511303,0.0002107852,0.0003063555,0.01024821],"category_scores_gemma":[0.00006252026,0.00009903443,0.0001074044,0.0003257994,0.0001646724,0.0004451361,0.000286701,0.0005790623,0.002605289],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003418972,"about_ca_system_score_gemma":0.0002690961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007731189,"about_ca_topic_score_gemma":0.002488025,"domain_scores_codex":[0.9999759,0.000003597587,7.949201e-7,0.000002860813,0.00001230808,0.000004509614],"domain_scores_gemma":[0.9999803,0.000008519608,0.000001866992,6.501982e-7,0.00000331998,0.000005220891],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002385659,0.00008932148,0.0005144034,0.001609582,0.00001439051,0.001371163,0.000194619,0.0009409461,0.1665063,0.04642004,0.1141024,0.6679983],"study_design_scores_gemma":[0.00001999513,0.0001399866,0.001934466,0.0003057896,0.0000145745,0.002371082,0.000169897,0.0005338468,0.01469857,0.008339938,0.9714587,0.00001316016],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01917398,0.7664715,0.006586371,0.009379239,0.002281148,0.00003990548,0.0003929147,0.0001832004,0.1954917],"genre_scores_gemma":[0.06923256,0.4905918,0.004780233,0.001912407,0.002041898,0.00006186561,0.0003692854,0.00007373931,0.4309362],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01024821,"threshold_uncertainty_score":0.0342837,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005775211425703818,"score_gpt":0.2334487494460145,"score_spread":0.2276735380203107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}