{"id":"W4283762428","doi":"10.1016/b978-0-323-91706-3.00011-4","title":"The tumor microenvironment of colorectal cancer liver metastases: Molecular mediators and future therapeutic targets","year":2022,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"","keywords":"Immune system; Metastasis; Colorectal cancer; Tumor microenvironment; Cancer research; Homeostasis; Liver cancer; Cancer; Biology; Medicine; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001220381,0.0003009857,0.0002726464,0.00003676548,0.0001645411,0.00001797776,0.0002274829,0.0001009323,0.0004889425],"category_scores_gemma":[0.000003204397,0.000218998,0.0001939453,0.000008076441,0.000291173,0.00000154889,0.0002986368,0.0002197244,0.00000430112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007472139,"about_ca_system_score_gemma":0.000169074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001010677,"about_ca_topic_score_gemma":0.0001660569,"domain_scores_codex":[0.9987321,0.00006210853,0.0002164544,0.0004037228,0.0003173583,0.0002682141],"domain_scores_gemma":[0.9993393,0.00001659582,0.0001744534,0.0003276266,0.00003046096,0.000111561],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003898865,0.00003262731,0.00005660425,0.0000801225,0.001894618,0.00008827548,0.0001070565,0.000001391495,0.03475457,0.0006673557,0.0004544974,0.961473],"study_design_scores_gemma":[0.000451654,0.0003362764,0.00006306665,0.00001560284,0.000190787,0.00001596034,0.00002202921,5.389835e-7,0.02306573,0.0002140284,0.9754256,0.0001987299],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"other","genre_scores_codex":[0.02930028,0.6677596,0.000002165563,0.000294251,0.0008555237,0.002675006,0.002395486,0.00001668615,0.296701],"genre_scores_gemma":[0.1025861,0.2314681,0.0002639607,0.001381021,0.001609808,0.001907833,0.0012643,0.0004762281,0.6590426],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.9749711,"threshold_uncertainty_score":0.8930481,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005775211425703818,"score_gpt":0.2334487494460145,"score_spread":0.2276735380203107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}