{"id":"W4283792195","doi":"10.1155/2022/8566970","title":"Enhancement of Mitochondrial Function by the Neurogenic Molecule NSI-189 Accompanies Reversal of Peripheral Neuropathy and Memory Impairment in a Rat Model of Type 2 Diabetes","year":2022,"lang":"en","type":"article","venue":"Journal of Diabetes Research","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"National Institutes of Health","keywords":"Peripheral neuropathy; Peripheral; Memory impairment; Function (biology); Medicine; Mitochondrion; Neuroscience; Diabetes mellitus; Chemistry; Internal medicine; Biology; Endocrinology; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002312885,0.0008622808,0.0006012634,0.0006496063,0.000244179,0.0002590755,0.000467533,0.00043772,0.001590824],"category_scores_gemma":[0.0001039104,0.0002160102,0.0004314933,0.0003613496,0.0004332987,0.0003647444,0.0001955635,0.001348134,0.000267894],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004756518,"about_ca_system_score_gemma":0.0004421932,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001776819,"about_ca_topic_score_gemma":0.003065178,"domain_scores_codex":[0.9998537,0.0000148849,0.00001877132,0.00002982016,0.00003841575,0.000044422],"domain_scores_gemma":[0.9997888,0.0000112913,0.00008404191,0.00001979065,0.00002669526,0.00006936662],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001823177,0.0004209501,0.0004212885,0.00009614614,0.00001994417,0.0000870576,0.00002309691,0.00008778284,0.9944226,0.00004834204,0.0000663903,0.002483221],"study_design_scores_gemma":[0.000258096,0.009049681,0.01454378,0.00002959645,0.00008289645,0.000278748,0.0001011615,0.0006654806,0.9738859,0.00005119093,0.001039559,0.00001398272],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963458,0.001247326,0.0009748514,0.0001021965,0.00005270771,0.00005045989,0.000478547,0.00008842257,0.0006596741],"genre_scores_gemma":[0.9926221,0.002022847,0.001690913,0.00008730801,0.00002069324,0.0001191092,0.0008951362,0.00001835115,0.00252334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001776819,"threshold_uncertainty_score":0.005321801,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02951926943224337,"score_gpt":0.3005128039330529,"score_spread":0.2709935345008095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}