{"id":"W4283794496","doi":"10.1016/j.ecl.2022.01.003","title":"High-Density Lipoprotein and Cardiovascular Disease—Where do We Stand?","year":2022,"lang":"en","type":"review","venue":"Endocrinology and Metabolism Clinics of North America","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Mendelian randomization; Atherosclerotic cardiovascular disease; Medicine; Disease; Internal medicine; Lipoprotein; Cholesterol; Endocrinology; High-density lipoprotein; Cardiology; Biology; Genetics; Gene; Genetic variants","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001473931,0.00154568,0.003584471,0.004073578,0.0005129375,0.002906326,0.001240371,0.002701197,0.007538506],"category_scores_gemma":[0.00204595,0.0005326188,0.0009867939,0.005250504,0.0008657592,0.003221348,0.001600345,0.003554647,0.002885798],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001360385,"about_ca_system_score_gemma":0.003953373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004392028,"about_ca_topic_score_gemma":0.01072423,"domain_scores_codex":[0.9995555,0.0001046073,0.00008373865,0.00006587305,0.0001379648,0.00005224084],"domain_scores_gemma":[0.9990925,0.0003308153,0.0001914661,0.00001895556,0.0002215659,0.0001447056],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002057755,0.00009741974,0.0003490396,0.02583787,0.0002817265,0.0001812213,0.00006518918,0.0001958416,0.0003247681,0.002681998,0.135949,0.8338302],"study_design_scores_gemma":[0.0001272994,0.0001601298,0.001783875,0.02139254,0.0007723962,0.0008327055,0.0001705148,0.0001256037,0.00007282419,0.002342211,0.9721779,0.00004207131],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000131125,0.9988341,0.00001544883,0.0005129758,0.0004164529,0.000001276821,0.000007429873,0.000002619955,0.0001965709],"genre_scores_gemma":[0.0001600712,0.9983221,0.00004456191,0.0006240669,0.0006226646,0.000002935994,0.00001171408,6.253895e-7,0.0002112672],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007538506,"threshold_uncertainty_score":0.02521878,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03353377088255131,"score_gpt":0.3015222799173763,"score_spread":0.267988509034825,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}