{"id":"W4283809270","doi":"10.1002/cbic.202200357","title":"Cover Feature: Identification of Genes Essential for Sulfamate and Fluorine Incorporation During Nucleocidin Biosynthesis (ChemBioChem 15/2022)","year":2022,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Metalloenzymes and iron-sulfur proteins","field":"Energy","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Biosynthesis; Gene; Chemistry; Enzyme; Biochemistry; Nucleoside; Gene cluster; Streptomyces; Combinatorial chemistry; Stereochemistry; Computational biology; Biology; Genetics; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004302914,0.0002579577,0.0003560379,0.0001327482,0.0003508701,0.00005833599,0.0002689365,0.0001277761,0.0004806349],"category_scores_gemma":[0.0001024666,0.0002866406,0.000168536,0.0003316123,0.00008848961,0.0001668008,0.0002893515,0.0001426992,0.00001179016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000097119,"about_ca_system_score_gemma":0.00004369349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007776288,"about_ca_topic_score_gemma":0.00001037704,"domain_scores_codex":[0.9982323,0.0000586128,0.0005075998,0.0005554096,0.0003473967,0.0002986981],"domain_scores_gemma":[0.9987833,0.00004953843,0.0004740503,0.000486434,0.000120117,0.00008653593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001964195,0.0001280362,0.0001234393,0.0003394116,0.00008945888,0.000001834512,0.0001612018,0.0000983045,0.9927892,0.002956628,0.001112757,0.002003317],"study_design_scores_gemma":[0.000963281,0.00006323421,0.0007772048,0.00001287443,0.00007988208,0.0000129086,0.0002027842,0.000938593,0.9890362,0.0006144585,0.006997874,0.0003007078],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961634,0.001731814,0.0003605823,0.0003719459,0.0002762902,0.0005126215,0.0001487544,0.0000802189,0.0003544276],"genre_scores_gemma":[0.9936433,0.0001607707,0.0007806093,0.00003467571,0.0002375166,0.0002696881,0.0003340293,0.00006573679,0.004473685],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005885117,"threshold_uncertainty_score":0.9999586,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008335050896558895,"score_gpt":0.2117306238624778,"score_spread":0.2033955729659189,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}