{"id":"W4283814783","doi":"10.1139/bcb-2022-0027","title":"Decursin ameliorates carbon-tetrachloride-induced liver fibrosis by facilitating ferroptosis of hepatic stellate cells","year":2022,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Liver physiology and pathology","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Shanghai University of Traditional Chinese Medicine; National Natural Science Foundation of China","keywords":"Sirius Red; Hepatic stellate cell; Hepatic fibrosis; Reactive oxygen species; Chemistry; Fibrosis; Carbon tetrachloride; Glutathione; GPX4; Lipid peroxidation; Internal medicine; Endocrinology; Glutathione peroxidase; Biochemistry; Oxidative stress; Biology; Medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001201485,0.0004748289,0.0005540047,0.0003997089,0.0001349982,0.0001283833,0.0001456717,0.0003066644,0.0007918492],"category_scores_gemma":[0.0001026154,0.0001196712,0.0002078514,0.0001000249,0.0002018357,0.0001867088,0.0001689136,0.0005205584,0.0001258626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001388069,"about_ca_system_score_gemma":0.0001713069,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002611769,"about_ca_topic_score_gemma":0.0006094101,"domain_scores_codex":[0.9999228,0.00002045354,0.00001212349,0.000008179873,0.00001706266,0.00001941276],"domain_scores_gemma":[0.9999356,0.000007320216,0.00002171699,0.00000596211,0.000009513297,0.00001990031],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001027118,0.0002911887,0.0002208811,0.0001475304,0.0000171418,0.0001132356,0.00002232316,0.0001703419,0.9924723,0.00005311743,0.00008282931,0.005382045],"study_design_scores_gemma":[0.0001480449,0.003778811,0.004755032,0.00001596349,0.00004392886,0.0002811438,0.00004640007,0.0009034387,0.9879349,0.00007937181,0.002006917,0.000006043586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958354,0.002005696,0.00101241,0.0001403958,0.00004279449,0.0000478344,0.0001224528,0.00008073354,0.0007122906],"genre_scores_gemma":[0.9946349,0.001531449,0.001444994,0.000119273,0.00002319684,0.00005948123,0.0003001066,0.00001136211,0.001875296],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007918492,"threshold_uncertainty_score":0.002649009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01188161952929346,"score_gpt":0.2323980808962411,"score_spread":0.2205164613669477,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}