{"id":"W4283814834","doi":"10.1038/s41467-022-31443-9","title":"Atypical sideways recognition of CD1a by autoreactive γδ T cell receptors","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Allergy and Infectious Diseases; Monash Biomedicine Discovery Institute, Monash University; National Health and Medical Research Council; National Institutes of Health; Australian Synchrotron; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Wellcome Trust; Australian Nuclear Science and Technology Organisation","keywords":"T-cell receptor; Cell biology; Receptor; CD3; T cell; Antigen; Epitope; Biology; Antigen-presenting cell; CD8; Chemistry; Immune system; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008302942,0.00024458,0.0001732829,0.0001652976,0.0001687803,0.0004762754,0.0002890154,0.0003001544,0.002439104],"category_scores_gemma":[0.0001268248,0.0001821784,0.0002420394,0.0001102424,0.0001877967,0.0002367826,0.0004294192,0.0004852919,0.0008796318],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002347078,"about_ca_system_score_gemma":0.00008152819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000182507,"about_ca_topic_score_gemma":0.0002416796,"domain_scores_codex":[0.9998329,0.0000282762,0.00000719065,0.00003985553,0.0000460395,0.00004584951],"domain_scores_gemma":[0.9998993,0.00001638141,0.00001937881,0.00002474858,0.00001419138,0.00002602653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001022398,0.00001074732,0.0006326707,0.00001403953,0.000005871661,0.0002006079,0.00001946599,0.0002152506,0.9971393,0.0003102208,0.00008046267,0.00126924],"study_design_scores_gemma":[0.00003736279,0.0003372823,0.01928385,0.00001973012,0.00002599926,0.003879451,0.0002308808,0.007927748,0.9628446,0.0008549439,0.004533669,0.00002449552],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996466,0.0003229624,0.001346116,0.00003527396,0.00001348392,0.00000265539,0.00002849773,0.00002424439,0.001760723],"genre_scores_gemma":[0.9984416,0.00009818191,0.0006752489,0.00003781328,0.000004230117,0.000003401543,0.00004743403,0.000005849158,0.0006861287],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002439104,"threshold_uncertainty_score":0.008159637,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01540546781307134,"score_gpt":0.2538765111099232,"score_spread":0.2384710432968518,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}