{"id":"W4283825355","doi":"10.1002/cbic.202200361","title":"The Total Synthesis of Glycolipids from <i>Streptococcus pneumoniae</i> and a Re‐evaluation of Their Immunological Activity**","year":2022,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor","funders":"Natural Sciences and Engineering Research Council of Canada; Windsor Cancer Centre Foundation; Compute Canada; University of Windsor","keywords":"CD1D; Glycolipid; Biology; Antigen; Major histocompatibility complex; Natural killer T cell; Immune system; Streptococcus pneumoniae; Glycosphingolipid; T-cell receptor; Receptor; Microbiology; Immunology; Biochemistry; Bacteria; T cell; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005672573,0.0001217316,0.0002262129,0.00003765753,0.0002859048,0.000007575281,0.0001583704,0.0001068761,0.001067545],"category_scores_gemma":[0.0002232251,0.00008983188,0.0001105205,0.0001072904,0.0002356126,0.00004907731,0.0002041148,0.0002829001,0.0000107759],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006724555,"about_ca_system_score_gemma":0.00005429375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008563586,"about_ca_topic_score_gemma":0.000002240222,"domain_scores_codex":[0.9989177,0.000374354,0.0002639685,0.0002116679,0.00008226827,0.000150044],"domain_scores_gemma":[0.9987859,0.0005212971,0.0002632485,0.0003088159,0.0001124562,0.000008351865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003497505,0.0001492305,0.0001662063,0.000005175211,0.0001738882,9.390111e-8,0.0003059768,0.00000642925,0.9668047,0.00003609803,0.0008465424,0.03115589],"study_design_scores_gemma":[0.0005930075,0.0001699006,0.005115339,0.000012464,0.00007675551,0.00001036438,0.002358385,0.00006816172,0.9859704,0.00009017674,0.005447108,0.00008791396],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923964,0.003649073,0.000003812495,0.000250008,0.0009239522,0.000241212,0.00003152881,0.00002146066,0.002482523],"genre_scores_gemma":[0.9987642,0.0001292784,0.000002339866,0.000016903,0.00001531335,0.0001738121,0.00003960092,0.000008662006,0.0008498547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03106797,"threshold_uncertainty_score":0.9998456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01820460083179243,"score_gpt":0.2342650606646477,"score_spread":0.2160604598328552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}