{"id":"W4283825355","doi":"10.1002/cbic.202200361","title":"The Total Synthesis of Glycolipids from <i>Streptococcus pneumoniae</i> and a Re‐evaluation of Their Immunological Activity**","year":2022,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor","funders":"Natural Sciences and Engineering Research Council of Canada; Windsor Cancer Centre Foundation; Compute Canada; University of Windsor","keywords":"CD1D; Glycolipid; Biology; Antigen; Major histocompatibility complex; Natural killer T cell; Immune system; Streptococcus pneumoniae; Glycosphingolipid; T-cell receptor; Receptor; Microbiology; Immunology; Biochemistry; Bacteria; T cell; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001687901,0.0005715668,0.0002717346,0.000141858,0.0001519524,0.0003845875,0.0002815405,0.0002831427,0.0008492473],"category_scores_gemma":[0.0001740371,0.0001302007,0.0004082805,0.0002865605,0.000224702,0.0003719539,0.0002834339,0.0005450163,0.0004889328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004325531,"about_ca_system_score_gemma":0.0004782164,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006665104,"about_ca_topic_score_gemma":0.0007963364,"domain_scores_codex":[0.9998784,0.00001805499,0.000007933964,0.00002659425,0.00004297421,0.00002592865],"domain_scores_gemma":[0.9999329,0.000013125,0.00001857407,0.00001251031,0.00001178575,0.00001103778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001968493,0.00005161929,0.0002250679,0.0005591635,0.00003296088,0.0001000456,0.00002865346,0.00177912,0.9789291,0.001325428,0.0002212075,0.01655074],"study_design_scores_gemma":[0.000009985112,0.000241324,0.0002789464,0.00001527901,0.00002923273,0.0001135491,0.000007900651,0.001410037,0.9894837,0.0001785233,0.008222969,0.000008555873],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9419756,0.01161304,0.03519882,0.0002566532,0.0002136809,0.0001278242,0.001273164,0.0002563677,0.009084905],"genre_scores_gemma":[0.9479387,0.009047333,0.03796424,0.00009005768,0.00002308232,0.00009172012,0.001350928,0.0001025419,0.003391409],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008492473,"threshold_uncertainty_score":0.003138363,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01820460083179243,"score_gpt":0.2342650606646477,"score_spread":0.2160604598328552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}