{"id":"W4283826314","doi":"10.1093/cvr/cvac107","title":"Common disease-promoting signalling pathways in heart failure and atrial fibrillation: putative underlying mechanisms and potential therapeutic consequences","year":2022,"lang":"en","type":"letter","venue":"Cardiovascular Research","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; National Institutes of Health; Deutsche Forschungsgemeinschaft","keywords":"Atrial fibrillation; Heart failure; Medicine; Disease; Bioinformatics; Cardiology; Signal transduction; Heart disease; Signalling pathways; Internal medicine; Biology; Genetics; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002814191,0.0005449039,0.002041316,0.0004336501,0.001521668,0.002171178,0.0008010032,0.02088076,0.00246529],"category_scores_gemma":[0.01096649,0.0003364676,0.0009438459,0.0005419587,0.002172195,0.001902118,0.0008305546,0.01711169,0.001807621],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002088198,"about_ca_system_score_gemma":0.001533576,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009439812,"about_ca_topic_score_gemma":0.001855881,"domain_scores_codex":[0.9984999,0.00058094,0.0002347496,0.0001632505,0.0003572162,0.0001640211],"domain_scores_gemma":[0.9933385,0.00461311,0.0003529848,0.0002182569,0.0007905476,0.0006865185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001749,0.0002807571,0.00590119,0.0004164903,0.0001433265,0.01659953,0.0002678978,0.0003475048,0.002313854,0.01248288,0.8806592,0.07883845],"study_design_scores_gemma":[0.003639062,0.0008823175,0.01771555,0.000856617,0.0003123903,0.02336676,0.0008462561,0.003642831,0.001889985,0.1151481,0.8314896,0.0002104952],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.003281025,0.01012446,0.0003249434,0.9640266,0.01948226,0.00001818875,0.00008661162,0.00003263579,0.002623183],"genre_scores_gemma":[0.04499495,0.01433185,0.001198779,0.6418946,0.2923101,0.0001219919,0.0001044503,0.00002449286,0.005018753],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.02088076,"threshold_uncertainty_score":0.01515102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06955356540613655,"score_gpt":0.3268830740700087,"score_spread":0.2573295086638721,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}