{"id":"W4283829238","doi":"10.1136/thoraxjnl-2021-217389","title":"In vivo bronchial epithelial interferon responses are augmented in asthma on day 4 following experimental rhinovirus infection","year":2022,"lang":"en","type":"article","venue":"Thorax","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Asthma and Lung UK; FP7 Ideas: European Research Council; Medical Research Council; National Institute for Health and Care Research","keywords":"Rhinovirus; Medicine; Asthma; In vivo; Interferon; Immunology; Virus; Respiratory system; Innate immune system; Internal medicine; Immune system; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003816154,0.0002850797,0.0004865904,0.0003617752,0.0002630805,0.0004162056,0.00008781806,0.0005914819,0.001260318],"category_scores_gemma":[0.0004524571,0.0002533476,0.0002386452,0.0001444911,0.0003695003,0.0001541161,0.0002152581,0.0008155046,0.0003097506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002312426,"about_ca_system_score_gemma":0.000135014,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004796798,"about_ca_topic_score_gemma":0.0007367735,"domain_scores_codex":[0.9996786,0.0001049966,0.00001840361,0.00005468755,0.00005469089,0.00008871335],"domain_scores_gemma":[0.9996659,0.00007141134,0.00009267774,0.00004458723,0.00003266043,0.00009277431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002304429,0.0001584733,0.02540155,0.00004075493,0.00001870952,0.000340488,0.0001315906,0.00005467161,0.9693232,0.00001711942,0.00005165046,0.002157389],"study_design_scores_gemma":[0.00006192422,0.00528063,0.8229266,0.00001950413,0.00007394815,0.001099424,0.0004097784,0.0003376061,0.1690625,0.00007832897,0.0006320874,0.00001779943],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988708,0.0004571255,0.000144984,0.00002205451,0.00001042682,0.0000156882,0.00007866626,0.00001108123,0.0003891285],"genre_scores_gemma":[0.9990414,0.0001505215,0.0001282921,0.00002979755,0.00001150392,0.00002191829,0.0001986592,0.000003650136,0.0004142506],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001260318,"threshold_uncertainty_score":0.004216135,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01860469161273221,"score_gpt":0.3137144852307723,"score_spread":0.2951097936180401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}