{"id":"W4283837217","doi":"10.1159/000525548","title":"Endotoxemic Shock: A Molecular Phenotype in Sepsis","year":2022,"lang":"en","type":"review","venue":"The Nephron journals/Nephron journals","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Iridian Spectral Technologies (Canada)","funders":"","keywords":"Sepsis; Medicine; Organ dysfunction; Phenotype; Shock (circulatory); Septic shock; Acute kidney injury; Inflammation; Narrative review; Immunology; Clinical phenotype; Intensive care medicine; Bioinformatics; Internal medicine; Gene; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005352346,0.000721916,0.001341541,0.002157075,0.0002081145,0.001091782,0.0005561411,0.0009732851,0.001267993],"category_scores_gemma":[0.0009928283,0.000186121,0.000347132,0.002488428,0.0006847435,0.0008663904,0.0005945273,0.001288702,0.0006686826],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005409788,"about_ca_system_score_gemma":0.001083234,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008884726,"about_ca_topic_score_gemma":0.00101255,"domain_scores_codex":[0.9997615,0.00005608356,0.00004614778,0.00004188712,0.00007577381,0.0000185623],"domain_scores_gemma":[0.9995896,0.0001917943,0.00009067404,0.000009347774,0.00009015444,0.00002835515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001106544,0.00003559708,0.000759497,0.03441589,0.0001687898,0.0003841759,0.0001414343,0.0002787737,0.0009752274,0.004294829,0.03207937,0.9263557],"study_design_scores_gemma":[0.00003015453,0.000197434,0.00619297,0.02890631,0.0005320014,0.01012639,0.0003707858,0.0001559318,0.0006305874,0.004879917,0.9479218,0.00005579925],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000571563,0.9995005,0.0000248681,0.0001493347,0.0001055141,0.000001101244,0.00000355806,0.000001361067,0.0001566142],"genre_scores_gemma":[0.000781873,0.9988072,0.00004246995,0.0001115536,0.0001665892,0.000002350919,0.000007859006,4.171071e-7,0.00007976172],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002157075,"threshold_uncertainty_score":0.004241884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0454859410555131,"score_gpt":0.3272708094606402,"score_spread":0.2817848684051271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}