{"id":"W4284668081","doi":"10.1371/journal.ppat.1010681","title":"Serum bridging molecules drive candidal invasion of human but not mouse endothelial cells","year":2022,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Clinical and Translational Science Institute, University of California, Los Angeles; National Center for Advancing Translational Sciences; National Institute of Dental and Craniofacial Research; National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Biology; Candida albicans; Microbiology; Endothelial stem cell; Endocytosis; Vitronectin; Cell biology; Candida glabrata; Receptor; Integrin; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002114609,0.0002042298,0.0001715418,0.0001607529,0.000152227,0.0004551428,0.0002209158,0.0003149369,0.001569921],"category_scores_gemma":[0.0001611856,0.000139718,0.0001881722,0.0001536772,0.0001292595,0.0001178381,0.0002114295,0.0004712867,0.0003754338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003105433,"about_ca_system_score_gemma":0.0001830874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001474971,"about_ca_topic_score_gemma":0.001683342,"domain_scores_codex":[0.9997541,0.00005248955,0.00001717081,0.0000341895,0.00006536343,0.00007667133],"domain_scores_gemma":[0.9998835,0.00002902709,0.00002437347,0.00002433246,0.00001681555,0.00002199666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006728993,0.00005177244,0.0001470329,0.00002023289,0.000003792475,0.00004113014,0.00003199131,0.00007022536,0.9982333,0.0002690135,0.00009458024,0.000969667],"study_design_scores_gemma":[0.00001402074,0.0002636917,0.002471714,0.000008471226,0.000008111602,0.0002108339,0.00005723989,0.001775044,0.9920492,0.00005522548,0.003082554,0.000003800487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944437,0.0008448063,0.001728539,0.0001032556,0.00001886527,0.00002269425,0.000255004,0.0000668818,0.002516282],"genre_scores_gemma":[0.9953843,0.0004641971,0.001474623,0.00006464955,0.000003565144,0.00002328487,0.0003874839,0.00001217499,0.002185669],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001569921,"threshold_uncertainty_score":0.005251944,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02413529420656748,"score_gpt":0.2516715354219236,"score_spread":0.2275362412153561,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}