{"id":"W4284701169","doi":"10.3389/fphys.2022.915390","title":"Nutritional Regulation of Muscle Stem Cells in Exercise and Disease: The Role of Protein and Amino Acid Dietary Supplementation","year":2022,"lang":"en","type":"review","venue":"Frontiers in Physiology","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"CHIST-ERA; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Agencia Nacional de Investigación y Desarrollo; Agenția Națională pentru Cercetare și Dezvoltare; Egg Farmers of Canada; CHEO Research Institute; University of Ottawa","keywords":"Skeletal muscle; Progenitor cell; Myocyte; Biology; Stem cell; Endurance training; Adaptive response; Regeneration (biology); Internal medicine; Endocrinology; Cell biology; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004050365,0.0004585316,0.001069504,0.00089347,0.0002066099,0.0009095225,0.0004330705,0.0008267802,0.001413984],"category_scores_gemma":[0.0003180429,0.0001645215,0.0005840264,0.000729036,0.000376581,0.0007117083,0.0006435543,0.0007275594,0.0003783627],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005518587,"about_ca_system_score_gemma":0.00058776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001053991,"about_ca_topic_score_gemma":0.00155766,"domain_scores_codex":[0.9997924,0.00004704954,0.0000351438,0.00004754997,0.00005185795,0.00002599978],"domain_scores_gemma":[0.9998637,0.00004867131,0.00003031313,0.000004195879,0.00003897888,0.00001406715],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001172923,0.0002961584,0.002877665,0.04741011,0.000632709,0.001593018,0.0005117881,0.0008634607,0.1309113,0.00716916,0.008695378,0.7978663],"study_design_scores_gemma":[0.0001278015,0.001922992,0.04032607,0.01050418,0.001374893,0.004471721,0.0008759529,0.001245212,0.04174662,0.007844391,0.889411,0.0001491783],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005326603,0.992343,0.0006809675,0.0004117739,0.0001768155,0.00001005154,0.00005375859,0.00001439664,0.0009825268],"genre_scores_gemma":[0.0220094,0.9743188,0.001441673,0.0003554442,0.0002060488,0.00003507396,0.0001122657,0.000007534175,0.001513767],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001413984,"threshold_uncertainty_score":0.004730225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01113075998508434,"score_gpt":0.2455119039123622,"score_spread":0.2343811439272779,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}