{"id":"W4284892562","doi":"10.51731/cjht.2022.384","title":"Platform, Basket, and Umbrella Trial Designs: Stakeholder Perspectives of Novel Therapeutics","year":2022,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"Science, Research, and Medicine","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Impact; Telus (Canada); Canadian Agency for Drugs and Technologies in Health; University of Manitoba; University of Toronto","funders":"","keywords":"Clinical trial; Protocol (science); Stakeholder engagement; Medicine; Alternative medicine; Stakeholder; Medical physics; Engineering ethics; Public relations; Engineering; Internal medicine; Political science; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001794327,0.00009573559,0.0004111459,0.0009065975,0.0003091385,0.00001071342,0.0002545616,0.00006530614,0.00005090149],"category_scores_gemma":[0.0005787931,0.00007227693,0.00005385458,0.0005095969,0.0006521835,0.00006592618,0.00003339945,0.0006634173,1.780264e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003918874,"about_ca_system_score_gemma":0.005469954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001777564,"about_ca_topic_score_gemma":0.0004530882,"domain_scores_codex":[0.9985154,0.00004231172,0.0004551288,0.0001370586,0.0004387583,0.0004112979],"domain_scores_gemma":[0.9990115,0.0001225163,0.0003023844,0.0001974203,0.0002043969,0.0001618325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"qualitative","study_design_scores_codex":[0.007613016,0.0006716367,0.01058435,0.0005771521,0.00037559,0.0005586953,0.02740387,0.00004479269,0.004990357,0.007244814,0.007024629,0.9329111],"study_design_scores_gemma":[0.06414415,0.02793122,0.01460264,0.000587252,0.0001329871,0.003497536,0.7435897,0.0002140155,0.001918675,0.002441546,0.1405879,0.0003524254],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.889107,0.08139518,0.0003628732,0.02788407,0.000330409,0.0005848402,0.00002483381,0.0000298622,0.0002809317],"genre_scores_gemma":[0.9969109,0.001689525,0.0007157884,0.0005329168,0.00002507352,0.000006635632,7.89373e-7,0.000009885128,0.0001084633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9325587,"threshold_uncertainty_score":0.9703463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3202342750032946,"score_gpt":0.3883024218095185,"score_spread":0.06806814680622392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}