{"id":"W4284894578","doi":"10.1186/s13059-022-02716-9","title":"scSTEM: clustering pseudotime ordered single-cell data","year":2022,"lang":"en","type":"article","venue":"Genome biology","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Cancer Institute; National Institutes of Health","keywords":"Biology; Human genetics; Cluster analysis; Computational biology; Genome Biology; Evolutionary biology; Computational genomics; Genetics; Genomics; Computer science; Artificial intelligence; Genome; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001308302,0.0009697561,0.0009137135,0.002387255,0.0008453336,0.00188991,0.001362113,0.000785038,0.0059015],"category_scores_gemma":[0.005531106,0.0005633107,0.001432825,0.002399785,0.000593006,0.001057305,0.00115293,0.001541687,0.004136315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007437181,"about_ca_system_score_gemma":0.002160256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0033167,"about_ca_topic_score_gemma":0.008688003,"domain_scores_codex":[0.9993114,0.00009148707,0.00006653179,0.0002502665,0.0002178196,0.00006257062],"domain_scores_gemma":[0.9981816,0.0006480499,0.0001870914,0.0004533758,0.0004063356,0.0001236419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.002018044,0.000407213,0.03383126,0.00404955,0.001177096,0.001275105,0.001932956,0.1323998,0.2861731,0.03809347,0.1393783,0.3592641],"study_design_scores_gemma":[0.0001685993,0.0002604112,0.01339951,0.0001888252,0.0001591471,0.0007201746,0.0006217783,0.6687336,0.1331029,0.06147386,0.1208858,0.0002854395],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.04135162,0.0006377547,0.8503835,0.0002879415,0.0003502358,0.0004309315,0.06029495,0.0442495,0.002013483],"genre_scores_gemma":[0.1065111,0.0005550287,0.7745805,0.0003308006,0.0001054364,0.001436432,0.1085214,0.005766764,0.002192529],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.0059015,"threshold_uncertainty_score":0.01974243,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04464286254573301,"score_gpt":0.2457821154735761,"score_spread":0.2011392529278431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}