{"id":"W4284895340","doi":"10.1155/2022/9673512","title":"Fibroblast Growth Factor 19 Improves LPS‐Induced Lipid Disorder and Organ Injury by Regulating Metabolomic Characteristics in Mice","year":2022,"lang":"en","type":"article","venue":"Oxidative Medicine and Cellular Longevity","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Shanghai Municipal Education Commission; National Natural Science Foundation of China; Science and Technology Commission of Shanghai Municipality; Natural Science Foundation of Shanghai","keywords":"FGF19; Oxidative stress; FGF21; Fibroblast growth factor; Lipopolysaccharide; Malondialdehyde; Biology; Sepsis; Linoleic acid; Metabolomics; Endocrinology; Internal medicine; Pharmacology; Biochemistry; Chemistry; Immunology; Medicine; Fatty acid; Receptor; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004624335,0.000294664,0.0004059924,0.0001241259,0.0002384966,0.00002447737,0.0002034844,0.0001113656,0.0001345025],"category_scores_gemma":[0.0005718724,0.0002656819,0.00003930393,0.0001970093,0.000270918,0.00001842373,0.0005869128,0.0004238627,0.00000157991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004037538,"about_ca_system_score_gemma":0.00006823752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003420135,"about_ca_topic_score_gemma":0.00003807061,"domain_scores_codex":[0.9979272,0.0003792788,0.0003562757,0.0006474509,0.0002973202,0.0003925007],"domain_scores_gemma":[0.9992229,0.00008355133,0.0001717976,0.0002579828,0.00006907886,0.0001946277],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001804057,0.0000689011,0.01859078,0.0001052272,0.0000423464,0.00000465077,0.0004023335,1.063001e-7,0.9779354,0.00002748554,0.0006278289,0.002014534],"study_design_scores_gemma":[0.001929198,0.0018345,0.05259506,0.00007093892,0.00003454057,0.00001759316,0.001509727,0.000123794,0.9344597,0.00004419608,0.006842566,0.000538192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975218,0.0009407092,0.0002000603,0.0006255344,0.00005443346,0.0003883201,0.0001736054,0.00001259939,0.00008289923],"genre_scores_gemma":[0.9985051,0.0001685464,0.00006878881,0.000177269,0.000162444,0.00004218504,0.0004750277,0.00004101148,0.000359698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0434757,"threshold_uncertainty_score":0.9999796,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01200459952996342,"score_gpt":0.2548445520125994,"score_spread":0.242839952482636,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}