{"id":"W4284895340","doi":"10.1155/2022/9673512","title":"Fibroblast Growth Factor 19 Improves LPS‐Induced Lipid Disorder and Organ Injury by Regulating Metabolomic Characteristics in Mice","year":2022,"lang":"en","type":"article","venue":"Oxidative Medicine and Cellular Longevity","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Shanghai Municipal Education Commission; National Natural Science Foundation of China; Science and Technology Commission of Shanghai Municipality; Natural Science Foundation of Shanghai","keywords":"FGF19; Oxidative stress; FGF21; Fibroblast growth factor; Lipopolysaccharide; Malondialdehyde; Biology; Sepsis; Linoleic acid; Metabolomics; Endocrinology; Internal medicine; Pharmacology; Biochemistry; Chemistry; Immunology; Medicine; Fatty acid; Receptor; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002583094,0.0006527095,0.0005573935,0.000967709,0.0002431128,0.0003315532,0.000229234,0.0004092719,0.001455486],"category_scores_gemma":[0.0001445836,0.0002169326,0.0006126781,0.0003370505,0.0002885982,0.000374244,0.0002868448,0.001296278,0.0002211208],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002853813,"about_ca_system_score_gemma":0.0003424171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007872761,"about_ca_topic_score_gemma":0.00130519,"domain_scores_codex":[0.9998121,0.00002652033,0.00002014949,0.00004000226,0.00005029115,0.0000509676],"domain_scores_gemma":[0.999853,0.000007952784,0.00005369274,0.00001075553,0.00001782572,0.0000567963],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002250167,0.0003581276,0.001191679,0.0001500773,0.00005532516,0.0001378615,0.00003688818,0.0002189071,0.9875748,0.0001362533,0.0002337826,0.007656279],"study_design_scores_gemma":[0.0003933066,0.005773668,0.02758766,0.00005298006,0.0003038073,0.0004258783,0.0001414541,0.003990966,0.95215,0.0005118226,0.008631586,0.00003686124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984821,0.00416898,0.005826366,0.0005141276,0.0001073932,0.0001088207,0.002412059,0.0003915175,0.001649743],"genre_scores_gemma":[0.9798741,0.003863135,0.008128663,0.000373941,0.00004325086,0.0002874787,0.002409374,0.00009269911,0.004927358],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001455486,"threshold_uncertainty_score":0.004869103,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01200459952996342,"score_gpt":0.2548445520125994,"score_spread":0.242839952482636,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}