{"id":"W4284899212","doi":"10.1182/blood.2022016530","title":"Immune complications and their management in inherited and acquired bleeding disorders","year":2022,"lang":"en","type":"article","venue":"Blood","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; Spark Therapeutics; National Institutes of Health; Riley Children's Foundation; Canadian Institutes of Health Research; Regeneron Pharmaceuticals; Lilly Endowment; Eli Lilly and Company","keywords":"Medicine; Bleeding diathesis; Immune system; Immunology; Intensive care medicine; Platelet","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006191317,0.0003116826,0.0004045364,0.0006535875,0.0003120617,0.0006065542,0.0003265531,0.0007162198,0.001171925],"category_scores_gemma":[0.001171742,0.00006135243,0.0002942246,0.0003289971,0.0002660968,0.0004890062,0.0006142714,0.001400149,0.0002637186],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002964225,"about_ca_system_score_gemma":0.0003952363,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002790377,"about_ca_topic_score_gemma":0.0003882617,"domain_scores_codex":[0.9997196,0.00009898681,0.00004482818,0.00002254967,0.00007069708,0.00004345352],"domain_scores_gemma":[0.9997301,0.00008071451,0.00007481977,0.000009571999,0.00004096799,0.00006378957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004295606,0.0002523347,0.005596144,0.001787393,0.00009897601,0.00806559,0.0002598411,0.0004772873,0.002089428,0.006505451,0.02124139,0.9531966],"study_design_scores_gemma":[0.0005981547,0.003311327,0.05674899,0.00844531,0.0005592584,0.1493841,0.001128121,0.002174933,0.003947753,0.02226433,0.7513386,0.00009917724],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03385033,0.9308919,0.00573043,0.0120381,0.001452951,0.00007352886,0.00005569943,0.00007926155,0.01582776],"genre_scores_gemma":[0.3613347,0.5999118,0.01099329,0.009949182,0.009247454,0.0002161711,0.0002793076,0.0000361787,0.008031822],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001171925,"threshold_uncertainty_score":0.003920436,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02533899978828071,"score_gpt":0.2834411590228502,"score_spread":0.2581021592345695,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}