{"id":"W4285008968","doi":"10.3389/fvets.2022.937866","title":"Enteric Escherichia coli O157:H7 in Cattle, and the Use of Mice as a Model to Elucidate Key Aspects of the Host-Pathogen-Microbiota Interaction: A Review","year":2022,"lang":"en","type":"review","venue":"Frontiers in Veterinary Science","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada; University of Alberta; University of Lethbridge","keywords":"Biology; Colonization; Host (biology); Escherichia coli; Microbiology; Pathogen; Outbreak; Colonisation resistance; Microbiome; Salmonella; Host adaptation; Immune system; Salmonella enterica; Bacteria; Immunology; Genetics; Gene; Virulence; Virology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001284823,0.0003054563,0.0009630558,0.0002428554,0.0001349428,0.00003504052,0.001384275,0.00008236209,0.000007615005],"category_scores_gemma":[0.001166975,0.0002007414,0.000213982,0.00193287,0.001136635,0.00002575174,0.002610564,0.0004091783,6.884671e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001467691,"about_ca_system_score_gemma":0.0009478064,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001038262,"about_ca_topic_score_gemma":0.00002231485,"domain_scores_codex":[0.9973307,0.0006538403,0.0006159307,0.0006745663,0.0003559233,0.0003691014],"domain_scores_gemma":[0.9985238,0.00007700148,0.0004051515,0.0008342455,0.00008955247,0.00007020467],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002714425,0.001303951,0.0004327046,0.08917761,0.000855946,0.0001642274,0.004326582,0.0009156094,0.5843267,0.0004222457,0.01516276,0.3001972],"study_design_scores_gemma":[0.0003172689,0.0005102734,0.0001341112,0.007005061,0.00007980341,0.00008994235,0.0001134554,0.0003484394,0.0001016986,0.000009810167,0.9910105,0.0002795974],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03015389,0.9669828,0.00008675515,0.0001747784,0.0004330981,0.001851091,0.000112606,0.000002782456,0.0002022217],"genre_scores_gemma":[0.002256097,0.9940767,0.002763548,0.0003509647,0.00001554272,0.0002976321,0.00001236915,0.00002183797,0.0002053319],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9758478,"threshold_uncertainty_score":0.8185998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06664173748652741,"score_gpt":0.3411021804559772,"score_spread":0.2744604429694498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}