{"id":"W4285008968","doi":"10.3389/fvets.2022.937866","title":"Enteric Escherichia coli O157:H7 in Cattle, and the Use of Mice as a Model to Elucidate Key Aspects of the Host-Pathogen-Microbiota Interaction: A Review","year":2022,"lang":"en","type":"review","venue":"Frontiers in Veterinary Science","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Agriculture and Agri-Food Canada","funders":"Agriculture and Agri-Food Canada; University of Alberta; University of Lethbridge","keywords":"Biology; Colonization; Host (biology); Escherichia coli; Microbiology; Pathogen; Outbreak; Colonisation resistance; Microbiome; Salmonella; Host adaptation; Immune system; Salmonella enterica; Bacteria; Immunology; Genetics; Gene; Virulence; Virology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009759059,0.0008377961,0.001316906,0.003150009,0.0002067621,0.001121673,0.0006946185,0.001066528,0.001878504],"category_scores_gemma":[0.001196469,0.0002971517,0.0008207784,0.002334326,0.0004874597,0.001377174,0.0004927736,0.001146997,0.0006939978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000534793,"about_ca_system_score_gemma":0.001680896,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001851776,"about_ca_topic_score_gemma":0.002659127,"domain_scores_codex":[0.9996279,0.00009968137,0.00008900944,0.00005955539,0.00009695194,0.00002672313],"domain_scores_gemma":[0.9990591,0.000513234,0.0001957236,0.00001909032,0.0001554803,0.00005745819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002289407,0.000156662,0.001117859,0.09741069,0.0003419959,0.0003462789,0.0002512861,0.0004273865,0.006175551,0.002409158,0.02650232,0.864632],"study_design_scores_gemma":[0.00002596088,0.0005139946,0.005100307,0.02598786,0.001028954,0.002369723,0.000237376,0.0001520758,0.001483697,0.001336459,0.9617129,0.00005061446],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002114616,0.998894,0.0001080944,0.000197821,0.0001341943,0.000006837217,0.00002729477,0.000005080359,0.0004152279],"genre_scores_gemma":[0.0007114062,0.9986284,0.000197935,0.0001662411,0.00009112935,0.000009867768,0.00003686006,0.000001298397,0.0001568933],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003150009,"threshold_uncertainty_score":0.006284237,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06664173748652741,"score_gpt":0.3411021804559772,"score_spread":0.2744604429694498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}