{"id":"W4285026485","doi":"10.1158/1078-0432.ccr-21-3817","title":"Molecular Subclasses of Clear Cell Ovarian Carcinoma and Their Impact on Disease Behavior and Outcomes","year":2022,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Calgary","funders":"National Cancer Institute; Medical Research Council; National Institutes of Health; BC Cancer Foundation; Servier; Cancer Institute NSW; Department of Health and Social Care; Evans Medical Foundation; National Institute for Health and Care Research; National Health and Medical Research Council; American Society of Hematology; Cancer Research UK; Michael Smith Health Research BC; Cycle for Survival; Bristol-Myers Squibb; AstraZeneca; Damon Runyon Cancer Research Foundation; NIHR Cambridge Biomedical Research Centre; Breast Cancer Research Foundation","keywords":"Disease; Ovarian carcinoma; Ovarian cancer; Carcinoma; Medicine; Oncology; Pathology; Internal medicine; Biology; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007953891,0.0001221861,0.0002167756,0.00004910882,0.0001453079,0.00001960079,0.0001812082,0.00006483076,0.00008361874],"category_scores_gemma":[0.0001252032,0.00008970085,0.0001382201,0.00009203702,0.000255137,0.000002138297,0.0003873891,0.0003414367,6.550358e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003374043,"about_ca_system_score_gemma":0.0003307374,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002845308,"about_ca_topic_score_gemma":0.00001226991,"domain_scores_codex":[0.9984629,0.0003578336,0.0002497854,0.0004077649,0.0002719341,0.0002497896],"domain_scores_gemma":[0.9991229,0.0001272441,0.00005596661,0.0003729142,0.0000944757,0.0002265633],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003002549,0.0006564627,0.8818665,0.000125808,0.00009681137,0.00003739447,0.0001032748,0.0004691385,0.09792665,0.00006238659,0.001794554,0.01385848],"study_design_scores_gemma":[0.002347789,0.003333692,0.9546573,0.00002177019,0.00004960331,0.000004437992,0.0003666443,0.0008188363,0.03465214,0.0002214032,0.003225965,0.0003004167],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956304,0.003421849,0.000008220662,0.000320873,0.00006824392,0.000231666,0.0001868486,0.000004727583,0.0001271908],"genre_scores_gemma":[0.9987828,0.0006289931,0.00001898788,0.000164721,0.00006977276,0.0001108568,0.00002432842,0.00002376066,0.0001758128],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07279082,"threshold_uncertainty_score":0.3657894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08317223521178556,"score_gpt":0.4592187793860846,"score_spread":0.376046544174299,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}