{"id":"W4285026485","doi":"10.1158/1078-0432.ccr-21-3817","title":"Molecular Subclasses of Clear Cell Ovarian Carcinoma and Their Impact on Disease Behavior and Outcomes","year":2022,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Calgary","funders":"National Cancer Institute; Medical Research Council; National Institutes of Health; BC Cancer Foundation; Servier; Cancer Institute NSW; Department of Health and Social Care; Evans Medical Foundation; National Institute for Health and Care Research; National Health and Medical Research Council; American Society of Hematology; Cancer Research UK; Michael Smith Health Research BC; Cycle for Survival; Bristol-Myers Squibb; AstraZeneca; Damon Runyon Cancer Research Foundation; NIHR Cambridge Biomedical Research Centre; Breast Cancer Research Foundation","keywords":"Disease; Ovarian carcinoma; Ovarian cancer; Carcinoma; Medicine; Oncology; Pathology; Internal medicine; Biology; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008691041,0.000288005,0.0005590018,0.001351197,0.0003809682,0.000849675,0.0002420027,0.0003934775,0.001138805],"category_scores_gemma":[0.002406046,0.0001393876,0.0003398753,0.0005831181,0.0003513602,0.000339612,0.0004824824,0.0003099612,0.0002365928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003668241,"about_ca_system_score_gemma":0.0003317606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001165235,"about_ca_topic_score_gemma":0.001437239,"domain_scores_codex":[0.9994414,0.00008323135,0.00006923746,0.0001783575,0.0001451189,0.00008264541],"domain_scores_gemma":[0.998301,0.0003927138,0.0007341071,0.0001797118,0.0001806316,0.0002118625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004498736,0.00002459727,0.9871365,0.00002640634,0.00008155599,0.00007039992,0.00005035513,0.0001021036,0.008482556,0.00004278894,0.0000692617,0.003463562],"study_design_scores_gemma":[0.00001621921,0.0001247334,0.995695,0.00001119522,0.00005355519,0.0007872389,0.0001877013,0.0006563093,0.001874767,0.0001540742,0.0004334168,0.000005861775],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983385,0.0006518099,0.0003889977,0.00003083502,0.000004035777,0.00001805714,0.0003369433,0.000008037245,0.0002227597],"genre_scores_gemma":[0.9987997,0.0001096615,0.0002517081,0.00002242464,0.000008487375,0.00001535227,0.0007150216,0.000006717178,0.00007096159],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001351197,"threshold_uncertainty_score":0.004596353,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08317223521178556,"score_gpt":0.4592187793860846,"score_spread":0.376046544174299,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}