{"id":"W4285034525","doi":"10.1021/acsnano.2c03055","title":"Glioblastoma Associated Natural Killer Cell EVs Generating Tumour-Specific Signatures: Noninvasive GBM Liquid Biopsy with Self-Functionalized Quantum Probes","year":2022,"lang":"en","type":"article","venue":"ACS Nano","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Toronto Metropolitan University; St. Michael's Hospital","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Circulating tumor cell; Liquid biopsy; Cancer research; Immune system; Brain tumor; Extracellular vesicles; Cell; Biomarker; Medicine; Biology; Immunology; Pathology; Cancer; Cell biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002634708,0.0003527546,0.0002419231,0.00009400663,0.0005873203,0.00006703722,0.0004438956,0.0001655338,0.000253931],"category_scores_gemma":[0.0001308815,0.000328388,0.0001607158,0.0003644871,0.00009120567,0.00001334767,0.0003634033,0.0003872457,0.00002023776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001310241,"about_ca_system_score_gemma":0.0004326137,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007095259,"about_ca_topic_score_gemma":0.00001028214,"domain_scores_codex":[0.997656,0.0002856121,0.0003275273,0.0007192453,0.0005181959,0.00049343],"domain_scores_gemma":[0.9988035,0.00004581998,0.0002760275,0.000471906,0.0002040052,0.0001987405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009901657,0.0004298781,0.0001544496,0.00002117598,0.0001595061,0.0001363027,0.0001606305,0.001355857,0.9836051,0.0001489691,0.01280858,0.00002931525],"study_design_scores_gemma":[0.002934576,0.002239862,0.0001502105,0.00002819093,0.00009887552,0.0001474439,0.0004493884,0.0005354342,0.95014,0.00005168417,0.04239605,0.0008283165],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910066,0.007065522,0.0001486509,0.0001536731,0.0006626158,0.000467956,0.00006577931,0.0001076245,0.0003215506],"genre_scores_gemma":[0.9944053,0.00006193593,0.001204052,0.0005369353,0.000300473,0.0001875468,0.0006841925,0.00009158612,0.002527994],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0334652,"threshold_uncertainty_score":0.9999168,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004976303859096215,"score_gpt":0.2023189896274885,"score_spread":0.1973426857683923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}