{"id":"W4285042840","doi":"10.1186/s12863-022-01068-4","title":"α-Gal antigen-deficient rabbits with GGTA1 gene disruption via CRISPR/Cas9","year":2022,"lang":"en","type":"article","venue":"BMC Genomic Data","topic":"Xenotransplantation and immune response","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"National Key Research and Development Program of China; National Institutes for Food and Drug Control","keywords":"Epitope; CRISPR; Antigen; Immune system; Biology; Gene; Cas9; Molecular biology; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009923319,0.0008430218,0.0007723729,0.0008369719,0.0003328273,0.0006733512,0.0007976176,0.001084678,0.001976357],"category_scores_gemma":[0.0006481672,0.0004747102,0.0009463514,0.0003418095,0.0007295023,0.0004992642,0.0007101247,0.00129644,0.001099238],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000409392,"about_ca_system_score_gemma":0.0004845652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006587065,"about_ca_topic_score_gemma":0.0005547048,"domain_scores_codex":[0.9987175,0.0001513137,0.0002220481,0.0003709387,0.000356042,0.0001821178],"domain_scores_gemma":[0.9993324,0.0000717544,0.0002938803,0.0001123883,0.00006560816,0.0001239738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001395712,0.00006581072,0.000401694,0.00007381171,0.00001652408,0.000255725,0.00005921776,0.0000994279,0.9959267,0.0004490476,0.0001000278,0.002412374],"study_design_scores_gemma":[0.00009204698,0.0007263781,0.00179597,0.00002912894,0.0001130964,0.002612308,0.00005151519,0.00224325,0.98234,0.0001836311,0.009785017,0.00002763227],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9110708,0.001872596,0.07936159,0.0004368941,0.0003097054,0.000610129,0.001014227,0.00113506,0.004188925],"genre_scores_gemma":[0.9330441,0.0024824,0.0472163,0.0002899224,0.00006125392,0.0007443221,0.00164977,0.0003556586,0.01415622],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001976357,"threshold_uncertainty_score":0.006611645,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0527721662851223,"score_gpt":0.2978128702452709,"score_spread":0.2450407039601486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}