{"id":"W4285042840","doi":"10.1186/s12863-022-01068-4","title":"α-Gal antigen-deficient rabbits with GGTA1 gene disruption via CRISPR/Cas9","year":2022,"lang":"en","type":"article","venue":"BMC Genomic Data","topic":"Xenotransplantation and immune response","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"National Key Research and Development Program of China; National Institutes for Food and Drug Control","keywords":"Epitope; CRISPR; Antigen; Immune system; Biology; Gene; Cas9; Molecular biology; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000502943,0.0001627767,0.0002315106,0.0001357722,0.0002623418,0.00002768528,0.0004098121,0.0000316818,0.0009300301],"category_scores_gemma":[0.00002369691,0.0001425737,0.0000460127,0.000214231,0.00005105099,0.0001081606,0.0003122543,0.0002121541,0.0002287199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000119836,"about_ca_system_score_gemma":0.0003229207,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001002816,"about_ca_topic_score_gemma":0.00002925421,"domain_scores_codex":[0.9984257,0.000147131,0.0002847298,0.0004823951,0.0003736476,0.0002863842],"domain_scores_gemma":[0.998479,0.00004814819,0.00009925882,0.001223746,0.00003455861,0.0001152514],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01450303,0.001192765,0.03147699,0.0002673829,0.0002527377,0.0004150094,0.002134534,0.001528585,0.9283617,0.0001546251,0.01067323,0.009039464],"study_design_scores_gemma":[0.01275672,0.002289761,0.5170223,0.00008168117,0.0006816844,0.006139,0.002168211,0.02008655,0.01950443,0.00002063723,0.4182204,0.001028616],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.966471,0.00097072,0.02972038,0.0003498816,0.0002724644,0.0005710032,0.001086327,0.00008054748,0.0004777003],"genre_scores_gemma":[0.9869289,0.0001774556,0.004445097,0.0005849734,0.000097435,0.00003294765,0.006189765,0.00004487762,0.001498523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9088572,"threshold_uncertainty_score":0.9999833,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0527721662851223,"score_gpt":0.2978128702452709,"score_spread":0.2450407039601486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}