{"id":"W4285043434","doi":"10.1200/jco.22.00825","title":"Therapy for Stage IV Non–Small-Cell Lung Cancer Without Driver Alterations: ASCO Living Guideline","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":124,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kingston General Hospital; Princess Margaret Cancer Centre; Queen's University; University Health Network; Juravinski Cancer Centre","funders":"","keywords":"Nivolumab; Medicine; Ipilimumab; Atezolizumab; Oncology; Internal medicine; Guideline; Lung cancer; Chemotherapy; Cancer; Clinical trial; Randomized controlled trial; Immunotherapy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004167612,0.0009457871,0.001692052,0.002002548,0.0007987341,0.001543313,0.0036266,0.004618411,0.007203694],"category_scores_gemma":[0.01279697,0.0004678885,0.003419789,0.002083711,0.0005612308,0.001381275,0.001403796,0.003470455,0.004746788],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004070485,"about_ca_system_score_gemma":0.0134008,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03644109,"about_ca_topic_score_gemma":0.06647453,"domain_scores_codex":[0.9957379,0.001437914,0.0009517598,0.0002610723,0.001279906,0.0003313562],"domain_scores_gemma":[0.9930394,0.001182632,0.001246882,0.0001660251,0.003851845,0.0005132344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001029487,0.00007721535,0.001436315,0.0141576,0.000399518,0.000127546,0.000119717,0.0008006336,0.0004891487,0.002905429,0.8371391,0.1422446],"study_design_scores_gemma":[0.0005982307,0.0001213249,0.004959717,0.05744518,0.001203839,0.0004406351,0.000103149,0.0007148306,0.0003048661,0.004484811,0.9295526,0.00007082737],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"methods","genre_scores_codex":[0.005812487,0.459714,0.01742604,0.2942122,0.01767411,0.007315349,0.04890772,0.001313967,0.1476241],"genre_scores_gemma":[0.05156357,0.4690541,0.08591733,0.249379,0.0103985,0.01015418,0.07715166,0.0004811533,0.04590052],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.03644109,"threshold_uncertainty_score":0.07245797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1036405909442447,"score_gpt":0.4805426847156378,"score_spread":0.3769020937713932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}