{"id":"W4285083980","doi":"10.21203/rs.3.rs-1811920/v1","title":"Artichoke Phytocomplex Modulates Serum microRNAs in Patients Exposed to Asbestos: A First Step of a Phase II Clinical Trial","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Cynara cardunculus studies","field":"Agricultural and Biological Sciences","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Asbestos; microRNA; Clinical trial; Phase (matter); Medicine; Internal medicine; Oncology; Biology; Chemistry; Genetics; Gene; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002899509,0.0003248527,0.000936794,0.000136443,0.0005399022,0.00007862007,0.0009944761,0.0002600947,0.0009372601],"category_scores_gemma":[0.00156119,0.0001549948,0.0004932556,0.001006077,0.0002143984,0.00005717467,0.005977172,0.00138072,0.00002676097],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002752616,"about_ca_system_score_gemma":0.00008862247,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008891374,"about_ca_topic_score_gemma":0.00429452,"domain_scores_codex":[0.9941788,0.001182903,0.001147769,0.001064133,0.001546334,0.000880037],"domain_scores_gemma":[0.9974606,0.001106287,0.00024349,0.0003474165,0.0005688487,0.0002733258],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.09434416,0.04202656,0.5668589,0.001148228,0.0006127605,0.0001343897,0.005033636,0.0007186256,0.008450987,0.0001021741,0.02180002,0.2587695],"study_design_scores_gemma":[0.04074492,0.03852835,0.8629939,0.0007630872,0.00003348449,5.120948e-7,0.002489574,0.0004328285,0.0004172323,0.0004091981,0.05235074,0.0008361598],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910629,0.0002105267,5.752745e-7,0.001352472,0.000380178,0.005738073,0.0009483597,0.00004416625,0.0002627023],"genre_scores_gemma":[0.9977553,0.00009224804,0.0001083293,0.00004351663,0.0003676337,0.001158861,0.0002678965,0.00000499368,0.0002011899],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.296135,"threshold_uncertainty_score":0.999976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2066363529564797,"score_gpt":0.4366880203081956,"score_spread":0.230051667351716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}