{"id":"W4285091504","doi":"10.3389/fmolb.2022.975946","title":"Editorial: Mechanisms of Novel Drugs and Gene Modifiers in the Treatment of Cystic Fibrosis","year":2022,"lang":"en","type":"editorial","venue":"Frontiers in Molecular Biosciences","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Cystic fibrosis; Gene; Computational biology; Medicine; Biology; Pharmacology; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001062943,0.0003005845,0.000844087,0.0007252106,0.0000701164,0.00003124546,0.0005912604,0.0002845543,0.000008140186],"category_scores_gemma":[0.001219783,0.0002125586,0.0001531502,0.001090098,0.000779436,0.00006741743,0.0001075725,0.0003716355,1.225119e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003411339,"about_ca_system_score_gemma":0.0007066566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006672361,"about_ca_topic_score_gemma":0.00001797667,"domain_scores_codex":[0.995569,0.0002107515,0.0005650904,0.0006411775,0.002585104,0.0004288884],"domain_scores_gemma":[0.9984797,0.0005197899,0.0002868172,0.0004961117,0.0001219165,0.00009571372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001691595,0.001930876,0.0002643217,0.0007363591,0.000161691,0.00008107099,0.003779338,0.0004460242,0.1715282,0.0001437657,0.8160489,0.003187885],"study_design_scores_gemma":[0.01075488,0.01451275,0.0002307338,0.0008789062,0.0004870032,0.00001034271,0.01420679,0.002953598,0.07287448,0.003988085,0.8781743,0.0009281269],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.006516783,0.00561641,0.01160301,0.0001360465,0.9742908,0.001224449,0.0005381809,0.00001010505,0.00006419786],"genre_scores_gemma":[0.02476203,0.008766744,0.3017925,0.00005748016,0.6626667,0.000920737,0.0006579605,0.000137336,0.0002385921],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.3116242,"threshold_uncertainty_score":0.8667888,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007574143045475287,"score_gpt":0.2782140872235342,"score_spread":0.2706399441780589,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}