{"id":"W4285091504","doi":"10.3389/fmolb.2022.975946","title":"Editorial: Mechanisms of Novel Drugs and Gene Modifiers in the Treatment of Cystic Fibrosis","year":2022,"lang":"en","type":"editorial","venue":"Frontiers in Molecular Biosciences","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Cystic fibrosis; Gene; Computational biology; Medicine; Biology; Pharmacology; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004454814,0.004692331,0.003475158,0.002983369,0.002381108,0.004799884,0.00330671,0.01024472,0.02896585],"category_scores_gemma":[0.01130836,0.0009690537,0.002647581,0.0009000066,0.001567852,0.003831747,0.001214359,0.01064956,0.02310823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002282185,"about_ca_system_score_gemma":0.001815366,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008238586,"about_ca_topic_score_gemma":0.002203375,"domain_scores_codex":[0.9972435,0.0004497323,0.0003343835,0.0003350182,0.001409352,0.0002280374],"domain_scores_gemma":[0.9909993,0.002562163,0.0006864186,0.0002162311,0.003398004,0.002137962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007580618,0.00001436419,0.00001329853,0.0001750711,0.00001377937,0.00008580239,0.000004560145,0.00002559102,0.00009573044,0.0002245909,0.9944639,0.004807663],"study_design_scores_gemma":[0.0001166477,0.00005471737,0.0002019141,0.0002733315,0.00005268957,0.0003133639,0.00001863597,0.0001745397,0.0002248863,0.001036728,0.9975125,0.00002009002],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.00003815912,0.004423714,0.0001318323,0.0171973,0.9759824,0.00002580872,0.00007589339,0.00007119876,0.002053711],"genre_scores_gemma":[0.0004270198,0.003908393,0.0001135764,0.01289841,0.9685272,0.00002426081,0.00005691141,0.0000379502,0.01400614],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.02896585,"threshold_uncertainty_score":0.09690046,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007574143045475287,"score_gpt":0.2782140872235342,"score_spread":0.2706399441780589,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}