{"id":"W4285096804","doi":"10.5772/intechopen.105469","title":"Noncanonical (Non-R132H) IDH-Mutated Gliomas","year":2022,"lang":"en","type":"book-chapter","venue":"IntechOpen eBooks","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Isocitrate dehydrogenase; IDH1; IDH2; Glioma; Biology; Cancer research; Gene; Genetics; Mutation; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004282038,0.0004040252,0.0002293429,0.0003954402,0.0001441662,0.0006550396,0.0002352174,0.000297531,0.0312313],"category_scores_gemma":[0.0000961841,0.0001010042,0.0001573021,0.0003511512,0.0001836455,0.0005990849,0.0003184616,0.0006603927,0.0174162],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002681968,"about_ca_system_score_gemma":0.000212293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004119785,"about_ca_topic_score_gemma":0.001564704,"domain_scores_codex":[0.9999692,0.000002369041,0.000001326183,0.000006169941,0.00001742692,0.000003524274],"domain_scores_gemma":[0.9999747,0.000009401935,0.000002548972,0.000001751641,0.000005809813,0.000005831295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008048504,0.00005296566,0.0002232664,0.0009771512,0.000007885056,0.00107752,0.000207947,0.0002932971,0.01449888,0.02723708,0.2927464,0.6625971],"study_design_scores_gemma":[0.000004490513,0.0000251599,0.0006220521,0.000169081,0.000003877212,0.004229579,0.00003373275,0.000106974,0.001814477,0.005377353,0.9876088,0.000004358418],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.007162248,0.1595461,0.008389299,0.002670541,0.003905367,0.0000757099,0.0006893613,0.0006717836,0.8168896],"genre_scores_gemma":[0.01460003,0.05886712,0.004361538,0.0009820206,0.0006946172,0.00002954851,0.0004660087,0.0001425454,0.9198565],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.0312313,"threshold_uncertainty_score":0.1044791,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02386253414142437,"score_gpt":0.2768829501481723,"score_spread":0.253020416006748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}