{"id":"W4285096804","doi":"10.5772/intechopen.105469","title":"Noncanonical (Non-R132H) IDH-Mutated Gliomas","year":2022,"lang":"en","type":"book-chapter","venue":"IntechOpen eBooks","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Isocitrate dehydrogenase; IDH1; IDH2; Glioma; Biology; Cancer research; Gene; Genetics; Mutation; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002071176,0.0007044541,0.001140555,0.0004869862,0.0001857945,0.00007108648,0.0004036001,0.000521303,0.01042901],"category_scores_gemma":[0.00003918247,0.0006172786,0.0006481963,0.00004369022,0.0002161571,0.00003961681,0.000532268,0.001248962,0.001450454],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006768016,"about_ca_system_score_gemma":0.0006003755,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002709332,"about_ca_topic_score_gemma":0.00006653029,"domain_scores_codex":[0.9971219,0.00002567457,0.0007139017,0.0008851624,0.0007694595,0.0004838973],"domain_scores_gemma":[0.997902,0.0001392954,0.0003050415,0.001102055,0.0001750262,0.0003765601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003367828,0.002216603,0.0003702629,0.0007541853,0.01110155,0.08511464,0.001332884,0.000008420942,0.01771708,0.2600685,0.2257285,0.3922196],"study_design_scores_gemma":[0.002989017,0.001112063,0.00005775656,0.0006340442,0.0008905539,0.0009364301,0.00002555793,0.000008746714,0.006832447,0.002783544,0.9831368,0.000593023],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.001766152,0.0004558542,0.000008482601,0.0006575315,0.0005593201,0.001738839,0.0001435932,0.0002199866,0.9944502],"genre_scores_gemma":[0.1789245,0.0001760538,0.0004020199,0.001598887,0.000432885,0.0006040989,0.0004971623,0.0003693021,0.8169951],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.7574083,"threshold_uncertainty_score":0.9996278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02386253414142437,"score_gpt":0.2768829501481723,"score_spread":0.253020416006748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}