{"id":"W4285109569","doi":"10.7150/ntno.71946","title":"Ultrasound-triggered oxygen-loaded nanodroplets enhance and monitor cerebral damage from sonodynamic therapy","year":2022,"lang":"en","type":"article","venue":"Nanotheranostics","topic":"Ultrasound and Hyperthermia Applications","field":"Engineering","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Rehabilitation Institute; University of Toronto; Sunnybrook Health Science Centre","funders":"National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Sonodynamic therapy; Ultrasound; Reactive oxygen species; Oxygen; Chemistry; Edema; Microbubbles; Sonication; Medicine; Surgery; Radiology; Biochemistry; Chromatography","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007120891,0.000259988,0.0002497196,0.00007293524,0.0003798218,0.00008186111,0.0002970288,0.00009308764,0.0008527094],"category_scores_gemma":[0.0000238025,0.0002737114,0.00006771788,0.0002343531,0.00006752695,0.00008435814,0.00003332328,0.0002989563,0.00004420851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009937272,"about_ca_system_score_gemma":0.00002886004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009996831,"about_ca_topic_score_gemma":0.0000195831,"domain_scores_codex":[0.9987935,0.0000542293,0.0002580268,0.0003162249,0.0002460807,0.0003319664],"domain_scores_gemma":[0.9990053,0.0004210624,0.00005130109,0.000404604,0.00002714921,0.00009056002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002535392,0.00008264206,0.0008601099,0.000008352651,0.00009866633,0.000003875159,0.001105838,0.001376657,0.9895906,0.0001533973,0.0009546326,0.00573984],"study_design_scores_gemma":[0.007328688,0.0004109905,0.0488043,0.00006292493,0.0002089249,0.0001285324,0.001893206,0.02668603,0.4892948,0.006549885,0.4152839,0.003347846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915675,0.00272987,0.00321518,0.0001170172,0.0004309939,0.0003430293,0.0005837921,0.0004000707,0.0006125628],"genre_scores_gemma":[0.996478,0.0008265398,0.001394494,0.0002995195,0.0001906002,0.0001466635,0.0001426423,0.0001081962,0.0004133651],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5002958,"threshold_uncertainty_score":0.9999715,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006931235806064557,"score_gpt":0.2047348191566472,"score_spread":0.1978035833505826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}