{"id":"W4285298872","doi":"10.1007/978-1-0716-2409-8_5","title":"Combination of Endothelin-1 (ET-1) and L-NAME to Induce Murine Focal Cortical Stroke with Persistent Sensorimotor Deficits","year":2022,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; Heart and Stroke Foundation; University of Ottawa","funders":"","keywords":"Endothelin 1; Endothelin receptor; Stroke (engine); Medicine; Endothelins; Neuroscience; Anesthesia; Internal medicine; Psychology; Receptor; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004784099,0.001336471,0.001221864,0.001003109,0.0004043441,0.0004016637,0.0007324782,0.001162673,0.00191931],"category_scores_gemma":[0.0002674229,0.0003733029,0.0008593721,0.000507027,0.0008140788,0.000698257,0.0003671983,0.002311357,0.00043831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005826073,"about_ca_system_score_gemma":0.0009642026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001082111,"about_ca_topic_score_gemma":0.00236338,"domain_scores_codex":[0.9993802,0.00006575305,0.00007897834,0.0001351437,0.0001107078,0.0002291285],"domain_scores_gemma":[0.9996201,0.00004646483,0.0001050686,0.00004357846,0.00003567655,0.0001490833],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003670195,0.00157534,0.0002312773,0.0001959683,0.00006142985,0.0003651212,0.00006883808,0.0003708651,0.989272,0.0003570452,0.0002587621,0.003573109],"study_design_scores_gemma":[0.0004331637,0.006907353,0.001623386,0.00002312623,0.0001276115,0.000298574,0.00005128078,0.000950917,0.9876566,0.0001352496,0.001772534,0.00002009895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.9892217,0.001948481,0.004907947,0.0003142678,0.0005288812,0.0003173946,0.0006837447,0.0003045518,0.001772982],"genre_scores_gemma":[0.9884497,0.001474613,0.003376053,0.0001592395,0.00008771411,0.000477432,0.000541259,0.00004504079,0.005388988],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.00191931,"threshold_uncertainty_score":0.006420672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02227432967756634,"score_gpt":0.35954395879379,"score_spread":0.3372696291162237,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}