{"id":"W4285391219","doi":"10.3389/fonc.2022.924290","title":"Autophagy: A Versatile Player in the Progression of Colorectal Cancer and Drug Resistance","year":2022,"lang":"en","type":"review","venue":"Frontiers in Oncology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Sharjah Research Academy; Terry Fox Foundation","keywords":"Autophagy; Cancer research; Tumor microenvironment; Colorectal cancer; Metastasis; Epithelial–mesenchymal transition; Cancer; Immune system; Biology; Tumor progression; Medicine; Immunology; Apoptosis; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003800274,0.0003738325,0.0006396107,0.0007866732,0.0004776726,0.001274775,0.0002967691,0.0007528892,0.001573662],"category_scores_gemma":[0.0002243648,0.0001407153,0.0003878777,0.0006005323,0.0006933959,0.0007385066,0.0008191992,0.00112127,0.0006742371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006872853,"about_ca_system_score_gemma":0.000764716,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003882744,"about_ca_topic_score_gemma":0.0004948537,"domain_scores_codex":[0.9997274,0.00006980952,0.00001780293,0.0000504995,0.0000701044,0.00006438714],"domain_scores_gemma":[0.999868,0.00002115795,0.00003375035,0.000008475808,0.00003315734,0.00003539244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009298794,0.0001985847,0.009158218,0.007368225,0.0002285478,0.002250398,0.0009352613,0.001459943,0.1341867,0.06096423,0.06458743,0.7177327],"study_design_scores_gemma":[0.00006972803,0.0006006553,0.02166624,0.001301194,0.0001898284,0.00693194,0.000824964,0.001806776,0.03360407,0.02793864,0.9049729,0.00009314059],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03834709,0.9266947,0.006762865,0.01070029,0.00101141,0.00006177262,0.0005768331,0.0002968178,0.01554829],"genre_scores_gemma":[0.3218931,0.6586426,0.005460348,0.00226086,0.001224585,0.0001205588,0.000671905,0.00004908555,0.009676983],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001573662,"threshold_uncertainty_score":0.005264401,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02881740031390069,"score_gpt":0.3840842355874072,"score_spread":0.3552668352735065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}