{"id":"W4285392165","doi":"10.3390/cells11142193","title":"NF-κB p65 Attenuates Cardiomyocyte PGC-1α Expression in Hypoxia","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"Canadian Institutes of Health Research; Fondation de l’Hôpital Saint-Boniface","keywords":"Coactivator; Transactivation; Biology; Cell biology; Transcription factor; Peroxisome proliferator-activated receptor; Activator (genetics); Molecular biology; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002291105,0.0004835169,0.0004741534,0.0002133071,0.0001658241,0.0002091501,0.0002228129,0.0002635105,0.001603291],"category_scores_gemma":[0.0001204768,0.0002054605,0.0002901526,0.0001624515,0.0004648288,0.0002187542,0.0002488405,0.001034067,0.0003750066],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002032618,"about_ca_system_score_gemma":0.000345498,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006473591,"about_ca_topic_score_gemma":0.001082489,"domain_scores_codex":[0.9998247,0.00002511501,0.00001530766,0.00004161692,0.00003804164,0.00005526386],"domain_scores_gemma":[0.9998451,0.00001112385,0.00005436389,0.0000141136,0.00001171696,0.00006355122],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006471134,0.00008613877,0.00009549981,0.0001085385,0.000007997122,0.00004168908,0.00002239004,0.00006106132,0.9976592,0.00004900916,0.00009215977,0.001129303],"study_design_scores_gemma":[0.0002361089,0.002452349,0.007340483,0.0000390192,0.00005844914,0.0003777157,0.0001239592,0.001229073,0.9830741,0.000128557,0.004929496,0.00001061748],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836258,0.00668588,0.005791706,0.0004104562,0.0002974164,0.00007301394,0.0004977272,0.0003486341,0.002269433],"genre_scores_gemma":[0.9919391,0.002388233,0.001176104,0.0001351436,0.00004586545,0.00008350406,0.0004325333,0.0000419149,0.003757525],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001603291,"threshold_uncertainty_score":0.005363584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009098142302236297,"score_gpt":0.213269473373641,"score_spread":0.2041713310714047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}