{"id":"W4285395429","doi":"10.3390/cells11142185","title":"The Succinate Receptor SUCNR1 Resides at the Endoplasmic Reticulum and Relocates to the Plasma Membrane in Hypoxic Conditions","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Université de Sherbrooke; Centre Hospitalier Universitaire Sainte-Justine; Hôpital Maisonneuve-Rosemont; Université de Montréal; McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Endoplasmic reticulum; Cell biology; G protein-coupled receptor; Signal transduction; Biology; Receptor; STIM1; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006140707,0.0001210316,0.00009400015,0.00002448344,0.0009553019,0.00005288003,0.0003125659,0.00004551074,0.0003207539],"category_scores_gemma":[0.00006759219,0.00006733584,0.0000509862,0.0001393862,0.00009672397,0.000002335563,0.0003596348,0.0001599551,0.00003204794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002604999,"about_ca_system_score_gemma":0.00003623668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005230029,"about_ca_topic_score_gemma":0.0003124274,"domain_scores_codex":[0.998924,0.0002204306,0.0001809731,0.0002736307,0.0001443741,0.0002566085],"domain_scores_gemma":[0.9993448,0.000165617,0.0000599805,0.0003538405,0.00002710012,0.00004867052],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006396019,0.00001136942,0.00005101267,0.000004111344,0.00001634836,0.000002126066,0.0002820082,0.001257581,0.9837941,0.0003333175,0.01395345,0.0002306106],"study_design_scores_gemma":[0.0001772678,0.0001092896,0.00005904123,0.000004378593,0.000007266628,0.00001500448,0.000780441,0.0001132599,0.760555,0.0001041449,0.2379901,0.00008481932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925244,0.001130635,0.000009695348,0.004991333,0.0003855093,0.0003671838,0.00005354959,0.000007056893,0.0005306489],"genre_scores_gemma":[0.9920304,0.0007006038,0.00004135491,0.0005735958,0.00008267815,0.0001640846,0.00005006665,0.00001959647,0.006337598],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2240367,"threshold_uncertainty_score":0.7347507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004768266844654289,"score_gpt":0.2024659511757539,"score_spread":0.1976976843310996,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}