{"id":"W4285395429","doi":"10.3390/cells11142185","title":"The Succinate Receptor SUCNR1 Resides at the Endoplasmic Reticulum and Relocates to the Plasma Membrane in Hypoxic Conditions","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Université de Sherbrooke; Centre Hospitalier Universitaire Sainte-Justine; Hôpital Maisonneuve-Rosemont; Université de Montréal; McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Endoplasmic reticulum; Cell biology; G protein-coupled receptor; Signal transduction; Biology; Receptor; STIM1; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008766828,0.0002465984,0.0001839592,0.00008871657,0.00016251,0.0002255802,0.0001487602,0.0001813028,0.001010154],"category_scores_gemma":[0.00008957105,0.00009042144,0.0001730859,0.0001018163,0.0001910329,0.0003180314,0.0002166322,0.0002855961,0.0005519839],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003837797,"about_ca_system_score_gemma":0.0001529116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006263211,"about_ca_topic_score_gemma":0.0009510932,"domain_scores_codex":[0.9999036,0.000012982,0.000007802222,0.00002708991,0.00002711437,0.00002157851],"domain_scores_gemma":[0.9999397,0.000004743094,0.0000236419,0.000008147779,0.00001015691,0.00001370575],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000566041,0.000002568476,0.0001386394,0.00001752776,0.000001620361,0.00004197295,0.000005883328,0.00001892192,0.9991768,0.00009158743,0.00001400506,0.0004338235],"study_design_scores_gemma":[0.000006835103,0.00006677065,0.01008997,0.000005600793,0.00001035454,0.0006248646,0.00005605306,0.0007094807,0.9859278,0.0001034032,0.002394333,0.000004531531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903389,0.001697814,0.005784031,0.0001908955,0.00002274338,0.000007753034,0.0003533186,0.00007314015,0.001531496],"genre_scores_gemma":[0.9940714,0.0010761,0.001837823,0.000055599,0.000008061031,0.000009565611,0.0005290136,0.00001894091,0.002393362],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001010154,"threshold_uncertainty_score":0.003379285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004768266844654289,"score_gpt":0.2024659511757539,"score_spread":0.1976976843310996,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}